What happens when chitin becomes chitosan? A single-molecule study

被引:15
作者
Qian, Lu [2 ]
Zhang, Kai [1 ]
Guo, Xin [1 ]
Yu, Miao [1 ]
机构
[1] Sichuan Univ, Sch Mech Engn, Chengdu 610065, Peoples R China
[2] South China Univ Technol, Sch Mat Sci & Engn, Guangzhou 510641, Peoples R China
基金
中国博士后科学基金;
关键词
CHAIR-BOAT TRANSITIONS; FORCE SPECTROSCOPY; NATURAL CELLULOSE; WATER; ELASTICITY; MECHANICS; SOLVENT; EXTRACTION; MICROSCOPY; POLYMERS;
D O I
10.1039/d2ra07303j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chitin and chitosan are important support structures for many organisms and are important renewable macromolecular biomass resources. Structurally, with the removal of acetyl group, the solubility of chitosan is improved. However, the specific mechanism of solubility enhancement from chitin to chitosan is still unclear. In this study, the atomic force microscopy (AFM)-based single molecule force spectroscopy (SMFS) was used to obtain the single-chain mechanical behavior of chitin and chitosan. The results show that the hydrogen (H)-bonds' state, which can be influenced by the solvent, determines the degree of binding water (solubility) of polysaccharides, and that the binding water energy of a single chitosan chain is 6 times higher than that of chitin in water. Thus, H-bonding is the key to solubility enhancement and can be used to modulate the solubility properties of chitosan. It is expected that our studies can help to understand the structural and functional properties of chitin and chitosan at the single molecule level.
引用
收藏
页码:2294 / 2300
页数:7
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