Creating synthetic maize centromeres

被引:0
|
作者
Henderson, Ian R. [1 ]
机构
[1] Univ Cambridge, Dept Plant Sci, Cambridge, England
关键词
D O I
10.1038/s41477-023-01366-4
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A tethering approach based on a LexA-CENH3 fusion protein in maize activates functional centromeres at synthetic LexO repeat arrays. The synthetic centromeres cause fragmentation of the resulting dicentric chromosomes, resulting in stably inherited and self-sustaining neochromosomes.
引用
收藏
页码:379 / 380
页数:2
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