Creating synthetic maize centromeres

被引:0
|
作者
Henderson, Ian R. [1 ]
机构
[1] Univ Cambridge, Dept Plant Sci, Cambridge, England
关键词
D O I
10.1038/s41477-023-01366-4
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A tethering approach based on a LexA-CENH3 fusion protein in maize activates functional centromeres at synthetic LexO repeat arrays. The synthetic centromeres cause fragmentation of the resulting dicentric chromosomes, resulting in stably inherited and self-sustaining neochromosomes.
引用
收藏
页码:379 / 380
页数:2
相关论文
共 50 条
  • [1] Creating synthetic maize centromeres
    Ian R. Henderson
    Nature Plants, 2023, 9 : 379 - 380
  • [2] Synthetic maize centromeres transmit chromosomes across generations
    Dawe, R. Kelly
    Gent, Jonathan I. I.
    Zeng, Yibing
    Zhang, Han
    Fu, Fang-Fang
    Swentowsky, Kyle W. W.
    Kim, Dong Won
    Wang, Na
    Liu, Jianing
    Piri, Rebecca D. D.
    NATURE PLANTS, 2023, 9 (03) : 433 - +
  • [3] Synthetic maize centromeres transmit chromosomes across generations
    R. Kelly Dawe
    Jonathan I. Gent
    Yibing Zeng
    Han Zhang
    Fang-Fang Fu
    Kyle W. Swentowsky
    Dong Won Kim
    Na Wang
    Jianing Liu
    Rebecca D. Piri
    Nature Plants, 2023, 9 : 433 - 441
  • [4] Maize Centromeres: Structure, Function, Epigenetics
    Birchler, James A.
    Han, Fangpu
    ANNUAL REVIEW OF GENETICS, 2009, 43 : 287 - 303
  • [5] Distribution of retroelements in centromeres and neocentromeres of maize
    Mroczek, RJ
    Dawe, RK
    GENETICS, 2003, 165 (02) : 809 - 819
  • [6] Dynamic epigenetic states of maize centromeres
    Liu, Yalin
    Su, Handong
    Zhang, Jing
    Liu, Yang
    Han, Fangpu
    Birchler, James A.
    FRONTIERS IN PLANT SCIENCE, 2015, 6
  • [7] LOCATION OF THE CENTROMERES ON THE LINKAGE MAPS OF MAIZE
    ANDERSON, EG
    RANDOLPH, LF
    GENETICS, 1945, 30 (06) : 518 - 526
  • [8] Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize
    Liu, Yalin
    Su, Handong
    Zhang, Jing
    Shi, Lindan
    Liu, Yang
    Zhang, Bing
    Bai, Han
    Liang, Shuang
    Gao, Zhi
    Birchler, James A.
    Han, Fangpu
    PLANT CELL, 2020, 32 (10): : 3113 - 3123
  • [9] Heritable chromosome segregation by synthetic plant centromeres
    Dawe, R. K.
    MOLECULAR BIOLOGY OF THE CELL, 2023, 34 (02) : 165 - 165
  • [10] Gene Expression and Chromatin Modifications Associated with Maize Centromeres
    Zhao, Hainan
    Zhu, Xiaobiao
    Wang, Kai
    Gent, Jonathan I.
    Zhang, Wenli
    Dawe, R. Kelly
    Jiang, Jiming
    G3-GENES GENOMES GENETICS, 2016, 6 (01): : 183 - 192