Prevalence of life-sustaining treatment limitations in Polish very old intensive care patients (VIPs). A post-hoc analysis of two prospective observational studies

被引:0
作者
Pasieka, Pawel [1 ]
Surowka, Anna [1 ]
Fronczek, Jakub [1 ]
Skwara, Evan [1 ]
Czuczwar, Miroslaw [2 ]
Borys, Michal [2 ]
Krawczyk, Pawel [3 ]
Zietkiewicz, Miroslaw [3 ,4 ]
Nowak, Lukasz R. [5 ]
Zukowski, Maciej [6 ]
Kotfis, Katarzyna [6 ]
Cwyl, Katarzyna [7 ]
Skowronek, Jacek [8 ]
Solek-Pastuszka, Joanna [9 ]
Biernawska, Jowita [9 ]
Grudzien, Pawel [10 ]
Nasilowski, Pawel [11 ,12 ]
Popek, Natalia [13 ]
Cyrankiewicz, Waldemar [14 ]
Sierakowska, Katarzyna [14 ,15 ]
Mudyna, Wojciech [16 ]
Bialka, Szymon [17 ]
Studzinska, Dorota [1 ,18 ]
Bernas, Szymon [19 ]
Piechota, Mariusz [19 ]
Machala, Waldemar [20 ]
Sadowski, Lukasz [20 ]
Stefaniak, Jan [21 ]
Owczuk, Radoslaw [21 ]
Szymkowiak, Malgorzata [22 ]
Gawda, Ryszard [23 ]
Kozera, Natalia [24 ]
Adamik, Barbara [25 ]
Gozdzik, Waldemar [25 ]
Wieczorek, Agnieszka [26 ]
Janc, Jaroslaw [26 ]
Kluzik, Anna [27 ,28 ]
Trzebicki, Janusz [29 ]
Zatorski, Pawel [29 ]
Gola, Wojciech [30 ]
Hymczak, Hubert [31 ,32 ]
Krzych, Lukasz J. [33 ]
Czajka, Szymon [33 ]
Kosciuczuk, Urszula [34 ]
Kudlinski, Bartosz [35 ]
Flaatten, Hans [36 ]
Szczeklik, Wojciech [1 ]
机构
[1] Jagiellonian Univ, Ctr Intens Care & Perioperat Med, Med Coll, Krakow, Poland
[2] Med Univ Lublin, Dept Anaesthesiol & Intens Care 2, Lublin, Poland
[3] Jagiellonian Univ, Med Coll, Dept Anaesthesiol & Intens Care Med, Krakow, Poland
[4] John Paul II Hosp Krakow, Dept Anaesthesiol & Intens Care 2, Krakow, Poland
[5] 5th Mil Clin Hosp Krakow, Dept Intens Care & Anaesthesiol, Krakow, Poland
[6] Pomeranian Med Univ, Dept Anaesthesiol Intens Therapy & Acute Intoxica, Szczecin, Poland
[7] Reg Hlth Ctr Lubin, Anesthes & Intens Care Unit, Lubin, Poland
[8] St Raphael Hosp, Dept Anaesthesiol & Intens Care, Krakow, Poland
[9] Pomeranian Med Univ SPSK 1, Dept Clin Anesthesiol & Intens Therapy PUM, Szczecin, Poland
[10] E Szczekl Specialist Hosp Tarnow, Dept Anaesthesiol & Intens Therapy, Tarnow, Poland
[11] G Narutowicz Specialist Hosp Krakow, Dept Anaesthesiol & Intens Therapy, Krakow, Poland
[12] St Ann Hosp Miechow, Dept Anaesthesiol & Intens Care, Miechow, Poland
[13] S Zeromski Specialist Hosp Krakow, Dept Anaesthesiol & Intens Therapy, Krakow, Poland
[14] Antoni Jurasz Univ Hosp 1, Dept Anaesthesiol & Intens Therapy, Bydgoszcz, Poland
[15] Nicolaus Copernicus Univ, Dept Anaesthesiol & Intens Therapy, Ludwik Rydygier Coll Med, Bydgoszcz, Poland
[16] Ludw Rydygier Mem Specialized Hosp Krakow, Dept Anaesthesiol & Intens Therapy, Krakow, Poland
[17] Med Univ Silesia, Sch Med, Dept Anaesthesiol & Crit Care, Div Dent Zabrze, Zabrze, Poland
[18] St John Grande Hosp Krakow, Dept Anaesthesiol & Intens Care, Krakow, Poland
[19] Dr Wl Bieganski Reg Specialist Hosp Lodz, Ctr Artificial Extracorporeal Kidney & Liver Supp, Dept Anaesthesiol & Intens Therapy, Lodz, Poland
[20] Med Univ Lodz, Dept Anaesthesiol & Intens Therapy, Cent Teaching Hosp, Lodz, Poland
[21] Med Univ Gdansk, Fac Med, Dept Anaesthesiol & Intens Therapy, Gdansk, Poland
[22] Prov Hosp Poznan, Dept Anaesthesiol & Intens Care, Poznan, Poland
[23] Univ Opole, Inst Med Sci, Dept Anesthesiol & Intens Care, Opole, Poland
[24] Wroclaw Med Univ, Dept Anaesthesiol & Intens Therapy, Wroclaw, Poland
[25] Wroclaw Med Univ, Dept Anesthesiol & Intens Therapy, Wroclaw, Poland
[26] 4th Mil Hosp Wroclaw, Anaesthes & Intens Care Unit, Wroclaw, Poland
[27] Poznan Univ Med Sci, Dept Anaesthesiol Intens Therapy & Pain Treatment, Poznan, Poland
[28] Poznan Univ Med Sci, Dept Teaching Anaesthesiol & Intens Therapy, Poznan, Poland
[29] Med Univ Warsaw, Univ Clin Ctr, Infant Jesus Clin Hosp, Dept Anaesthesiol & Intens Care 1, Warsaw, Poland
[30] Jan Kochanowski Univ, Fac Med & Hlth Sci, Kielce, Poland
[31] John Paul II Hosp Krakow, Dept Anaesthesiol & Intens Care 1, Krakow, Poland
[32] Andrzej Frycz Modrzewski Krakow Univ, Fac Med & Hlth Sci, Krakow, Poland
[33] Med Univ Silesia, Univ Clin Ctr, Sch Med Katowice, Dept Anaesthesiol & Intens Care, Katowice, Poland
[34] Med Unibers Bialystok, Dept Anaesthesiol & Intens Therapy, Bialystok, Poland
[35] Univ Hosp Zielona Gora, Clin Dept Anaesthesiol & Intens Care, Zielona Gora, Poland
[36] Haukeland Hosp, Dept Anaesthesia & Intens Care, Bergen, Norway
关键词
Intensive care; Futile therapy; Ethics; End-of-life care; Observational study; Geriatric population; Limitations of life-sustaining treatment; VIP study; END; ICU; DECISIONS; MORTALITY; UNITS;
D O I
10.1016/j.jcrc.2023.154439
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Purpose: Several initiatives have recently focused on raising awareness about limitations of treatment in Poland. We aimed to assess if the propensity to limit LST among elderly patients in 2018-2019 increased compared to 2016-2017.Methods: We analysed Polish cohorts from studies VIP1 (October 2016 -May 2017) and VIP2 (May 2018 -May 2019) that enrolled critical patients aged >80. We collected data on demographics, clinical features limitations of LST. Primary analysis assessed factors associated with prevalence of limitations of LST, A secondary analysis explored differences between patients with and without limitations of LST.Results: 601 patients were enrolled. Prevalence of LST limitations was 16.1% in 2016-2017 and 20.5% in 2018-2019. No difference was found in univariate analysis (p = 0.22), multivariable model showed higher propensity towards limiting LST in the 2018-2019 cohort compared to 2016-2017 cohort (OR 1.07;95%CI, 1.01-1.14). There was higher mortality and a longer length of stay of patients with limitations of LST compared to the patients without limitations of LST. (11 vs. 6 days, p = 0.001).Conclusions: The clinicians in Poland have become more proactive in limiting LST in critically ill patients >= 80 years old over the studied period, however the prevalence of limitations of LST in Poland remains low.
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