Development of a prompt gamma-ray detector with an 8 x 8 array LaBr3(Ce) scintillator and a multi-pixel photon counter for boron neutron capture therapy

被引:0
|
作者
Okazaki, Keita [1 ,2 ]
Tanaka, Hiroki [2 ]
Takata, Takushi [2 ]
Kawabata, Shinji [3 ]
Hu, Naonori [3 ]
Matsubayashi, Nishiki [2 ,4 ]
Mukawa, Tetsuya [5 ]
Sakurai, Yoshinori [2 ]
Suzuki, Minoru [2 ]
机构
[1] Edogawa Hosp, 2-24-18 Higashikoiwa, Tokyo 1330052, Japan
[2] Kyoto Univ, Inst Integrated Radiat & Nucl Sci, 2 Asashironishi, Osaka 5900494, Japan
[3] Osaka Med & Pharmaceut Univ, 2-7 Daigakumachi, Takatsuki, Osaka 5698686, Japan
[4] Kyoto Univ Katsura, Kyoto Univ, Grad Sch Engn, Nishikyo Ku, Kyoto 6158540, Japan
[5] Sumitomo Heavy Ind Ltd, 2-1-1 Osaki, Shinagawa, Tokyo 1888585, Japan
来源
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2023年 / 1055卷
关键词
Boron neutron capture therapy; Pixelated-array scintillator; Real-time detection; Multi-pixel photon counter; Prompt gamma-ray analysis; TUMORS;
D O I
10.1016/j.nima.2023.168546
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A prompt gamma-ray detector for measuring the boron-10 concentration in real time for boron neutron capture therapy was researched. Our previous detector, which comprised a scintillator made from a slab of LaBr3(Ce) and an 8 x 8 array multi-pixel photon counter (MPPC), discriminated between 478 keV and 511 keV gamma rays. However, the spatial resolutions of the detector were not applicable to the detection of the boron concentration distribution. An 8 x 8 pixelated LaBr3(Ce) scintillator has been employed to improve the spatial resolution. In our previous report, the spatial resolution was improved by using the pixelated scintillator. However, the scintillation light produced in one pixel was sufficient to saturate the photon counts above 229 keV. Thus, a single peak was separated when the signals of all 64 channels were summed up. Many photon counts were eliminated to obtain the observed gamma-ray spectrum. In this study, an advanced 8 x 8 MPPC was employed, and the detector system had an energy resolution of 6.15% at 511 keV and spatial resolutions of 2.88 and 2.95 mm in the lateral and vertical directions, respectively, without eliminating any photon counts. In addition, the linearity of the photon counts of the 478 keV gamma rays and boron concentration was confirmed.
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页数:5
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