DEX, Delirium and Dilemma

被引：6

作者：

Magoon, Rohan ^{[1
]}

Mahajan, Shalvi ^{[2
]}

Jose, Jes ^{[3
,4
]}

机构：

[1] Atal Bihari Vajpayee Inst Med Sci ABVIMS & Dr Ram, Dept Cardiac Anaesthesia, New Delhi, India

[2] Post Grad Inst Med Educ & Res PGIMER, Dept Anaesthesia & Intens Care, Chandigarh, India

[3] Sri Jayadeva Inst Cardiovasc Sci & Res, Dept Cardiac Anesthesiol, Bengaluru, Karnataka, India

[4] Sri Jayadeva Inst Cardiovasc Sci & Res, Dept Cardiac Anesthesiol, Bannerghatta Main Rd,Phase 3,Jayanagara 9th Block, Bengaluru 560069, Karnataka, India

来源：

BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY | 2023年 / 38卷 / 02期

关键词：

Cardiac Surgery; Dexmedetomidine; Meta-Analysis; Delirium; Randomized Controlled Trials; CARDIAC-SURGERY; POSTOPERATIVE DELIRIUM; DEXMEDETOMIDINE; METAANALYSIS;

D O I：

10.21470/1678-9741-2022-0002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dexmedetomidine has been subjected to an extensive evaluation for its ' role in the prevention of postoperative delirium following cardiac surgery. In striking contrast to the preexisting meta-analysis supporting postoperative delirium-reduction with dexmedetomidine, few recently concluded multicentric large scale randomized controlled trials suggest otherwise. This article aims to present a nuanced perspective of the evolving controversy by attempting to decode the apparent incongruences in the literature accumulating off-late, which is particularly pertinent amidst an ever-escalating heterogeneity in the current research ecosystem.

引用

页码：305 / 308

页数：4

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