Diabetes Mellitus and Thyroid Cancers: Risky Correlation, Underlying Mechanisms and Clinical Prevention

被引：3
作者：
Wu, Rongqian [1 ,2 ,3 ]
Zhang, Junping [1 ,2 ,3 ]
Zou, Guilin [1 ,2 ,3 ]
Li, Shanshan [1 ]
Wang, Jinying [1 ]
Li, Xiaoxinlei [1 ]
Xu, Jixiong [1 ,2 ,3 ]
机构：
[1] Nanchang Univ, st Affiliated Hosp 1, Jiangxi Med Coll, Dept Endocrinol & Metab, Nanchang, Peoples R China
[2] Jiangxi Clin Res Ctr Endocrine & Metab Dis, Nanchang, Peoples R China
[3] Natl Clin Res Ctr Metab Dis, Jiangxi Branch, Nanchang, Peoples R China
来源：
DIABETES METABOLIC SYNDROME AND OBESITY | 2024年 / 17卷
关键词：
diabetes; thyroid cancer; underlying mechanisms; hypoglycemic drugs; CELL-GROWTH; INSULIN-RESISTANCE; COLORECTAL-CANCER; GLYCEMIC CONTROL; ASSOCIATION; EXPRESSION; METFORMIN; POLYMORPHISMS; ADIPONECTIN; FAMILY;
D O I：
10.2147/DMSO.S450321
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The incidences of thyroid cancer and diabetes are rapidly increasing worldwide. The relationship between thyroid cancer and diabetes is a popular topic in medicine. Increasing evidence has shown that diabetes increases the risk of thyroid cancer to a certain extent. This mechanism may be related to genetic factors, abnormal thyroid-stimulating hormone secretion, oxidative stress injury, hyperinsulinemia, elevated insulin-like growth factor-1 levels, abnormal secretion of adipocytokines, and increased secretion of inflammatory factors and chemokines. This article reviews the latest research progress on the relationship between thyroid cancer and diabetes, including the association between diabetes and the risk of developing thyroid cancer, its underlying mechanisms, and potential anti-thyroid cancer effects of hypoglycemic drugs. It providing novel strategies for the prevention, treatment, and improving the prognosis of thyroid cancer.
引用
收藏
页码：809 / 823
页数：15
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