Recent Advances in Micro- and Nano-Drug Delivery Systems Based on Natural and Synthetic Biomaterials

被引：25

作者：

Harun-Or-Rashid, Md. ^{[1
]}

Aktar, Most. Nazmin ^{[1
]}

Hossain, Md. Sabbir ^{[2
]}

Sarkar, Nadia ^{[2
]}

Islam, Md. Rezaul ^{[2
]}

Arafat, Md. Easin ^{[2
]}

Bhowmik, Shukanta ^{[1
]}

Yusa, Shin-ichi ^{[1
]}

机构：

[1] Univ Hyogo, Grad Sch Engn, Dept Appl Chem, 2167 Shosha, Himeji, Hyogo 6712280, Japan

[2] Daffodil Int Univ, Fac Allied Hlth Sci, Dept Pharm, Dhaka 1207, Bangladesh

来源：

POLYMERS | 2023年 / 15卷 / 23期

关键词：

natural polymers; synthetic polymers; drug delivery; copolymers; biomimetic; POLYESTER-BASED NANOPARTICLES; CHITOSAN-BASED NANOGELS; QUANTUM DOTS; CONTROLLED-RELEASE; POLYMERIC NANOPARTICLES; EXTRACELLULAR VESICLES; COATED NANOPARTICLES; ORAL BIOAVAILABILITY; PLGA NANOPARTICLES; TARGETED DELIVERY;

D O I：

10.3390/polym15234563

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell more easily, has advanced considerably in recent decades. Innovative medication delivery strategies use biodegradable and bio-reducible polymers, and progress in the field has been accelerated by future possible research applications. Natural polymers utilized in polymeric drug delivery systems include arginine, chitosan, dextrin, polysaccharides, poly(glycolic acid), poly(lactic acid), and hyaluronic acid. Additionally, poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic polymers, biodegradable polymers, and bioabsorbable polymers as well as biomimetic and bio-related polymeric systems and drug-free macromolecular therapies have been employed in polymeric drug delivery. Different synthetic and natural biomaterials are in the clinical phase to mitigate different diseases. Drug delivery methods using natural and synthetic polymers are becoming increasingly common in the pharmaceutical industry, with biocompatible and bio-related copolymers and dendrimers having helped cure cancer as drug delivery systems. This review discusses all the above components and how, by combining synthetic and biological approaches, micro- and nano-drug delivery systems can result in revolutionary polymeric drug and gene delivery devices.

引用

页数：44

共 284 条

[1] Controlled Drug Delivery Systems: Current Status and Future Directions [J].

Adepu, Shivakalyani ;

Ramakrishna, Seeram .

MOLECULES, 2021, 26 (19)

[2] Hybrid Quantum Dot as Promising Tools for Theranostic Application in Cancer [J].

Ahmad, Javed ;

Garg, Anuj ;

Mustafa, Gulam ;

Ahmad, Mohammad Zaki ;

Aslam, Mohammed ;

Mishra, Awanish .

ELECTRONICS, 2023, 12 (04)

[3] Intraperitoneal Route of Drug Administration: Should it Be Used in Experimental Animal Studies? [J].

Al Shoyaib, Abdullah ;

Archie, Sabrina Rahman ;

Karamyan, Vardan T. .

PHARMACEUTICAL RESEARCH, 2020, 37 (01)

[4]

Al-Arif S., 2011, J. Sel. Areas Nanotechnol., V2, P1

[5] Ligand-targeted therapeutics in anticancer therapy [J].

Allen, TM .

NATURE REVIEWS CANCER, 2002, 2 (10) :750-763

[6]

Alvani M., 2022, Med. Sci. J. Islam. Azad Univesity-Tehran Med. Branch, V32, P256, DOI [10.52547/iau.32.3.256, DOI 10.52547/IAU.32.3.256]

[7] Crosslinked ionic polysaccharides for stimuli-sensitive drug delivery [J].

Alvarez-Lorenzo, Carmen ;

Blanco-Fernandez, Barbara ;

Puga, Ana M. ;

Concheiro, Angel .

ADVANCED DRUG DELIVERY REVIEWS, 2013, 65 (09) :1148-1171

[8]

Amani A, 2019, IRAN J PHARM RES, V18, P125

[9] Preparation of composite with silica-coated nanoparticles of iron oxide spinels for applications based on magnetically induced hyperthermia [J].

Andrade, Angela L. ;

Fabris, Jose D. ;

Pereira, Marcio C. ;

Domingues, Rosana Z. ;

Ardisson, Jose D. .

HYPERFINE INTERACTIONS, 2013, 218 (1-3) :71-82

[10] Modulating Pharmacokinetics, Tumor Uptake and Biodistribution by Engineered Nanoparticles [J].

Arvizo, Rochelle R. ;

Miranda, Oscar R. ;

Moyano, Daniel F. ;

Walden, Chad A. ;

Giri, Karuna ;

Bhattacharya, Resham ;

Robertson, J. David ;

Rotello, Vincent M. ;

Reid, Joel M. ;

Mukherjee, Priyabrata .

PLOS ONE, 2011, 6 (09)

← 1 2 3 4 5 6 7 8 9 10 →