Issue on combined locoregional and systemic treatment for hepatocellular carcinoma

被引：5

作者：

Wu, Yi-Chia ^{[1
]}

Wakil, Ali ^{[2
]}

Salomon, Fayssa ^{[2
]}

Pyrsopoulos, Nikolaos ^{[2
]}

机构：

[1] St Peters Univ Hosp, New Brunswick, NJ USA

[2] Rutgers New Jersey Med Sch, Newark, NJ USA

来源：

HEPATOMA RESEARCH | 2023年 / 9卷

关键词：

Hepatocellular carcinoma; systemic therapy; locoregional therapy; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; ENDOTHELIAL GROWTH-FACTOR; RANDOMIZED PHASE-II; TRANSARTERIAL CHEMOEMBOLIZATION; RADIOFREQUENCY ABLATION; DOUBLE-BLIND; INFUSION CHEMOTHERAPY; COMBINATION THERAPY; PLUS SORAFENIB; EFFICACY;

D O I：

10.20517/2394-5079.2022.37

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Treatment for hepatocellular carcinoma (HCC) has been challenging as most patients present with late, advanced disease, where curative options are limited. For years, locoregional therapy (LRT) has been the first-line therapy for intermediate-stage HCC and sorafenib for advanced HCC. However, these treatments are often palliative since they are plagued by tumor recurrence or progression. Therefore, there is growing interest in combined therapy to utilize their respective strengths to produce synergistic effects. This review outlines past and current research on the efficacy and safety of combined LRT and systemic therapy.

引用

页数：15

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