Boundedness in a two-dimensional two-species cancer invasion haptotaxis model without cell proliferation

被引:0
作者
Dai, Feng [1 ,2 ,3 ]
Ma, Linjie [4 ]
机构
[1] Huazhong Univ Sci & Technol, Sch Math & Stat, Wuhan 430074, Hubei, Peoples R China
[2] Huazhong Univ Sci & Technol, Hubei Key Lab Engn Modeling & Sci Comp, Wuhan 430074, Hubei, Peoples R China
[3] Huazhong Univ Sci & Technol, Inst Artificial Intelligence, Wuhan 430074, Hubei, Peoples R China
[4] Beijing Normal Univ, Sch Math Sci, Lab Math & Complex Syst, Minist Educ, Beijing 100875, Peoples R China
来源
ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND PHYSIK | 2023年 / 74卷 / 02期
基金
中国博士后科学基金;
关键词
Cancer invasion; Haptotaxis; Tissue remodeling; Global existence; Boundedness; LARGE TIME BEHAVIOR; GLOBAL CLASSICAL-SOLUTIONS; ASYMPTOTIC-BEHAVIOR; CHEMOTAXIS SYSTEM; TUMOR INVASION; WEAK SOLUTIONS; BLOW-UP; EXISTENCE; TISSUE; SOLVABILITY;
D O I
10.1007/s00033-023-01942-w
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
in a bounded and smooth domain omega subset of R(2 )with homogeneous Neumann conditions, where chi 1, chi(2,) eta > 0, tau is an element of {0, 1}, f(v) is an element of C1 ([0, infinity); [0, infinity)) and f (0) = 0. It is well known that the absence of logistic source aggravates mathematical difficulties, which are overcome by constructing suitable Lyapunov functional. When the remodeling of ECM includes a competition with cancer cells (i.e., alpha(1) = alpha(2) = 1), we prove that the associated initial-boundary value problem of (SIC) with tau = 0 admits a globally bounded classical solution for suitably small eta, which complements the boundedness result on the homogenous Neumann problem of (SIC) with tau = 1 obtained in Dai and Liu (SIAM J Math Anal 54:1-35, 2022). When the competition with cancer cells is taken no account in the re-establishment of ECM (i.e., alpha(1) = alpha(2) = 0), we establish the global boundedness of classical solution to the corresponding initial-boundary value problem of (SIC) with tau is an element of {0,1} for arbitrarily large eta, which is completely new. These results reveal the significant difference on the global boundedness of classical solution for the case whether or not the competition with cancer cells is contained in the remodeling of ECM.
引用
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页数:26
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