Cyclodextrin nanoparticles in targeted cancer theranostics

被引:15
作者
Bose, Roshnee [1 ]
Jayawant, Maharsh [1 ]
Raut, Rajesh [2 ]
Lakkakula, Jaya [1 ,3 ]
Roy, Arpita [4 ]
Alghamdi, Saad [5 ]
Qusty, Naeem F. F. [5 ]
Sharma, Rohit [6 ]
Verma, Devvret [7 ]
Khandaker, Mayeen Uddin [8 ,9 ]
Almujally, Abdullah [10 ]
Tamam, Nissren [11 ]
Sulieman, Abdelmoneim [12 ]
机构
[1] Amity Univ Maharashtra, Amity Inst Biotechnol, Mumbai, Maharashtra, India
[2] Inst Sci, Dept Bot, Mumbai, Maharashtra, India
[3] Amity Univ Maharashtra, Amity Inst Biotechnol, Ctr Computat Biol & Translat Res, Mumbai, Maharashtra, India
[4] Sharda Univ, Sch Engn & Technol, Dept Biotechnol, Greater Noida, India
[5] Umm Al Qura Univ, Fac Appl Med Sci, Lab Med Dept, Mecca, Saudi Arabia
[6] Banaras Hindu Univ, Inst Med Sci, Fac Ayurveda, Dept Rasa Shastra & Bhaishajya Kalpana, Varanasi, Uttar Pradesh, India
[7] Graph Era Deemed Univ, Dept Biotechnol, Dehra Dun, Uttaranchal, India
[8] Sunway Univ, Ctr Appl Phys & Radiat Technol, Sch Engn & Technol, Petaling Jaya, Selangor, Malaysia
[9] Daffodil Int Univ, Fac Sci & Informat Technol, Dept Gen Educ Dev, Dhaka, Bangladesh
[10] King Faisal Specialist Hosp & Res Ctr, Dept Biomed Phys, Riyadh, Saudi Arabia
[11] Princess Nourah Bint Abdulrahman Univ, Coll Sci, Dept Phys, Riyadh, Saudi Arabia
[12] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Radiol & Med Imaging Dept, Alkharj, Saudi Arabia
关键词
cyclodextrin; imaging; theranostics; diagnosis; cancer; DRUG; DELIVERY; CORE; NANOTHERANOSTICS; AGGREGATION; STATISTICS;
D O I
10.3389/fphar.2023.1218867
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The field of cancer nanotheranostics is rapidly evolving, with cyclodextrin (CD)-based nanoparticles emerging as a promising tool. CDs, serving as nanocarriers, have higher adaptability and demonstrate immense potential in delivering powerful anti-cancer drugs, leading to promising and specific therapeutic outcomes for combating various types of cancer. The unique characteristics of CDs, combined with innovative nanocomplex creation techniques such as encapsulation, enable the development of potential theranostic treatments. The review here focuses mainly on the different techniques administered for effective nanotheranostics applications of CD-associated complex compounds in the domain of cancer treatments. The experimentations on various loaded drugs and their complex conjugates with CDs prove effective in in vivo results. Various cancers can have potential nanotheranostics cures using CDs as nanoparticles along with a highly efficient process of nanocomplex development and a drug delivery system. In conclusion, nanotheranostics holds immense potential for targeted drug delivery and improved therapeutic outcomes, offering a promising avenue for revolutionizing cancer treatments through continuous research and innovative approaches.
引用
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页数:20
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