An evolutionary deep learning soft sensor model based on random forest feature selection technique for penicillin fermentation process

Accurate and reliable measurement of key biological parameters during penicillin fermentation is of great significance for improving penicillin production. In this research context, a new hybrid soft sensor model method based on RF-IHHO-LSTM (random forest-improved Harris hawks optimization-long short-term memory) is proposed for penicillin fermentation processes. Firstly, random forest (RF) is used for feature selection of the auxiliary variables for penicillin. Next, improvements are made for the Harris hawks optimization (HHO) algorithm, including using elite opposition-based learning strategy (EOBL) in initialization to enhance the population diversity, and using golden sine algorithm (Gold-SA) in the search strategy to make the algorithm accelerate convergence. Then the long short-term memory (LSTM) network is constructed to build a soft sensor model of penicillin fermentation processes. Finally, the hybrid soft sensor model is used to the Pensim platform in simulation experimental research. The simulation test results show that the established soft sensor model, with high accuracy of measurement and good effect, can meet the actual requirements of engineering.(c) 2022 ISA. Published by Elsevier Ltd. All rights reserved.