Deformation of Transcatheter Heart Valve Following Valve-in-Valve Transcatheter Aortic Valve Replacement Implications for Hemodynamics

被引:18
作者
Fukui, Miho [1 ,2 ]
Sorajja, Paul [3 ,4 ]
Cavalcante, Joao L. [1 ,2 ]
Thao, Kiahltone R. [3 ]
Okada, Atsushi [3 ]
Sato, Hirotomo [3 ]
Wang, Cheng [3 ]
Koike, Hideki [1 ,2 ]
Hamid, Nadira [3 ,4 ]
Enriquez-Sarano, Maurice [3 ]
Lesser, John R. [3 ,4 ]
Bapat, Vinayak N. [3 ,4 ,5 ]
机构
[1] Minneapolis Heart Inst Fdn, Cardiovasc Imaging Res Ctr, Minneapolis, MN USA
[2] Minneapolis Heart Inst Fdn, Core Lab, Minneapolis, MN USA
[3] Minneapolis Heart Inst Fdn, Valve Sci Ctr, Minneapolis, MN USA
[4] Abbott NW Hosp, Minneapolis Heart Inst, Minneapolis, MN USA
[5] Abbott NW Hosp, Minneapolis Heart Inst Fdn, Minneapolis Heart Inst, Valve Sci Ctr, 800 East 28th St,Suite 300, Minneapolis, MN 55407 USA
关键词
balloon aortic valvuloplasty; BAV; computed tomography; CT; deformation; TAVR; transcatheter aortic valve replacement; valve-in-valve; EUROPEAN ASSOCIATION; BIOPROSTHETIC VALVE; HOSPITAL OUTCOMES; AMERICAN SOCIETY; IMPLANTATION; RECOMMENDATIONS; POSITION; UPDATE;
D O I
10.1016/j.jcin.2023.01.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) may be associated with adverse hemodynamics, which might affect clinical outcomes.OBJECTIVES This study sought to evaluate the extent and predictors of transcatheter heart valve (THV) deformity in ViV TAVR and the relation to postprocedural hemodynamics.METHODS We examined 53 patients who underwent ViV TAVR in surgical heart valves with self-expanding Evolut prostheses. THV deformation was examined using cardiac computed tomography prospectively performed 30 days after ViV TAVR, and correlated with 30-day echocardiographic hemodynamic data.RESULTS Near complete expansion of the functional portion of the implanted ViV prostheses (ie, >90%) was observed in 16 (30.2%) patients. Factors related to greater expansion of the functional portion and consequently larger neosinus volume were absence of polymer surgical frame, higher implantation and use of balloon aortic valvuloplasty or bioprosthetic valve fracture during the procedure (all P < 0.05). Underexpansion of the functional portion, but not the valve inflow frame, was closely associated with mean gradient and effective orifice area at 30 days on echocardiography, with and without adjustment for the sizes of the THV and surgical heart valve.CONCLUSIONS Underexpansion of the functional portion of THV prostheses is common during ViV TAVR, occurs more frequently with deep implantation and the presence of a polymer surgical stent frame, and is associated with worse postprocedural hemodynamics. Procedural techniques, such as higher implantation and balloon postdilatation, may be used to help overcome problems with THV underexpansion and improve clinical outcomes. (J Am Coll Cardiol Intv 2023;16:515-526)(c) 2023 by the American College of Cardiology Foundation.
引用
收藏
页码:515 / 526
页数:12
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