Dynamic Biobanking for Advancing Breast Cancer Research

被引：1

作者：

Abdollahyan, Maryam ^{[1
]}

Gadaleta, Emanuela ^{[1
]}

Asif, Millahat ^{[1
]}

Oscanoa, Jorge ^{[1
]}

Barrow-McGee, Rachel ^{[2
]}

Jones, Samantha ^{[2
]}

Jones, Louise J. ^{[2
]}

Chelala, Claude ^{[1
]}

机构：

[1] Queen Mary Univ London, Barts Canc Inst, Ctr Canc Biomarkers & Biotherapeut, London EC1M 6BQ, England

[2] Queen Mary Univ London, Barts Canc Inst, Ctr Tumour Biol, London EC1M 6BQ, England

来源：

JOURNAL OF PERSONALIZED MEDICINE | 2023年 / 13卷 / 02期

关键词：

breast cancer; translational research; precision medicine; electronic health records; genomics; health informatics; bioinformatics;

D O I：

10.3390/jpm13020360

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Longitudinal patient biospecimens and data advance breast cancer research through enabling precision medicine approaches for identifying risk, early diagnosis, improved disease management and targeted therapy. Cancer biobanks must evolve to provide not only access to high-quality annotated biospecimens and rich associated data, but also the tools required to harness these data. We present the Breast Cancer Now Tissue Bank centre at the Barts Cancer Institute as an exemplar of a dynamic biobanking ecosystem that hosts and links longitudinal biospecimens and multimodal data including electronic health records, genomic and imaging data, offered alongside integrated data sharing and analytics tools. We demonstrate how such an ecosystem can inform precision medicine efforts in breast cancer research.

引用

页数：12

共 31 条

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