Recent Advancements of LSPR Fiber-Optic Biosensing: Combination Methods, Structure, and Prospects

被引：37
作者：
Zhang, Hongxin [1 ]
Zhou, Xue [1 ]
Li, Xuegang [1 ,2 ,3 ]
Gong, Pengqi [1 ,2 ,3 ]
Zhang, Yanan [1 ,2 ,3 ]
Zhao, Yong [1 ,2 ,3 ]
机构：
[1] Northeastern Univ, Coll Informat Sci & Engn, Shenyang 110819, Peoples R China
[2] State Key Lab Synthet Automat Proc Ind, Shenyang 110819, Peoples R China
[3] Hebei Key Lab Micronano Precis Opt Sensing & Meas, Qinhuangdao 066004, Peoples R China
来源：
BIOSENSORS-BASEL | 2023年 / 13卷 / 03期
基金：
中国国家自然科学基金;
关键词：
LSPR; biosensor; label-free; optical fiber sensor; SURFACE-PLASMON RESONANCE; PLASTIC OPTICAL-FIBER; SILVER NANOPARTICLES; GOLD NANOPARTICLES; SENSOR; TECHNOLOGY; LAB; SENSITIVITY; FABRICATION; DEPOSITION;
D O I：
10.3390/bios13030405
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Fiber-optic biosensors based on localized surface plasmon resonance (LSPR) have the advantages of great biocompatibility, label-free, strong stability, and real-time monitoring of various analytes. LSPR fiber-optic biosensors have attracted extensive research attention in the fields of environmental science, clinical medicine, disease diagnosis, and food safety. The latest development of LSPR fiber-optic biosensors in recent years has focused on the detection of clinical disease markers and the detection of various toxic substances in the environment and the progress of new sensitization mechanisms in LSPR fiber-optic sensors. Therefore, this paper reviews the LSPR fiber-optic sensors from the aspects of working principle, structure, and application fields in biosensors. According to the structure, the sensor can be divided into three categories: traditional ordinary optical fiber, special shape optical fiber, and specialty optical fiber. The advantages and disadvantages of existing and future LSPR fiber-optic biosensors are discussed in detail. Additionally, the prospect of future development of fiber-optic biosensors based on LSPR is addressed.
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页数：29
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