The Frail-LESS (LEss Sitting and Sarcopenia in Frail older adults) intervention to improve sarcopenia and maintain independent living via reductions in prolonged sitting: a randomised controlled feasibility trial protocol

被引：9

作者：

Bailey, Daniel P. P. ^{[1
,2
]}

Kilbride, Cherry ^{[1
,3
]}

Harper, Jamie H. H. ^{[1
,2
]}

Victor, Christina ^{[4
]}

Brierley, Marsha L. L. ^{[1
]}

Hewson, David J. J. ^{[5
]}

Chater, Angel M. M. ^{[6
,7
]}

机构：

[1] Brunel Univ London, Ctr Phys Act Hlth & Dis, Kingston Lane, Uxbridge UB8 3PH, England

[2] Brunel Univ London, Dept Life Sci, Div Sport Hlth & Exercise Sci, Uxbridge UB8 3PH, England

[3] Brunel Univ London, Dept Hlth Sci, Div Physiotherapy & Phys Associates, Uxbridge UB8 3PH, England

[4] Brunel Univ London, Div Global Publ Hlth, Uxbridge UB8 3PH, England

[5] Univ Bedfordshire, Inst Hlth Res, Luton LU1 3JU, England

[6] Univ Bedfordshire, Inst Sport & Phys Act Res, Polhill Ave, Bedford MK41 9EA, England

[7] UCL, Ctr Behav Change, London WC1E 7HB, England

来源：

PILOT AND FEASIBILITY STUDIES | 2023年 / 9卷 / 01期

关键词：

Sarcopenia; Frailty; Sedentary behaviour; Prolonged sitting; Behaviour change; activPAL; BEHAVIOR-CHANGE WHEEL; UP SEDENTARY TIME; PHYSICAL PERFORMANCE; SAMPLE-SIZE; HEALTH; VALIDATION; ASSOCIATION; PREVALENCE; BREAKING; SCALE;

D O I：

10.1186/s40814-022-01225-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background Sarcopenia is a progressive and generalised loss of muscle mass and function with advancing age and is a major contributor to frailty. These conditions lead to functional disability, loss of independence, and lower quality of life. Sedentary behaviour is adversely associated with sarcopenia and frailty. Reducing and breaking up sitting should thus be explored as an intervention target for their management. The primary aim of this study, therefore, is to examine the feasibility, safety, and acceptability of conducting a randomised controlled trial (RCT) that evaluates a remotely delivered intervention to improve sarcopenia and independent living via reducing and breaking up sitting in frail older adults. Methods This mixed-methods randomised controlled feasibility trial will recruit 60 community-dwelling older adults aged & GE; 65 years with very mild or mild frailty. After baseline measures, participants will be randomised to receive the Frail-LESS (LEss Sitting and Sarcopenia in Frail older adults) intervention or serve as controls (usual care) for 6 months. Frail-LESS is a remotely delivered intervention comprising of tailored feedback on sitting, information on the health risks of excess sitting, supported goal setting and action planning, a wearable device that tracks inactive time and provides alerts to move, health coaching, and peer support. Feasibility will be assessed in terms of recruitment, retention and data completion rates. A process evaluation will assess intervention acceptability, safety, and fidelity of the trial. The following measures will be taken at baseline, 3 months, and 6 months: sitting, standing, and stepping using a thigh-worn activPAL4 device, sarcopenia (via hand grip strength, muscle mass, and physical function), mood, wellbeing, and quality of life. Discussion This study will determine the feasibility, safety, and acceptability of evaluating a remote intervention to reduce and break up sitting to support improvements in sarcopenia and independent living in frail older adults. A future definitive RCT to determine intervention effectiveness will be informed by the study findings.

引用

页数：12

共 78 条

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