A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

被引：4

作者：

Ma, Qing-yu ^{[1
]}

Li, Xiang ^{[1
]}

Zhou, Wei ^{[1
]}

Li, Xia-fen ^{[1
]}

Liu, Yi-chen ^{[1
]}

Feng, Gai-li ^{[1
]}

Tan, Hongwei ^{[1
]}

Zhang, Yuan ^{[1
,2
]}

Xing, Guo-wen ^{[1
]}

机构：

[1] Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China

[2] Beijing Normal Univ, Coll Chem, Key Lab Energy Convers & Storage Mat, Beijing 100875, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 68期

基金：

中国国家自然科学基金;

关键词：

PROBE; DNA;

D O I：

10.1039/d3cc02788k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.

引用

页码：10287 / 10290

页数：4