A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

被引：4
|
作者：
Ma, Qing-yu [1 ]
Li, Xiang [1 ]
Zhou, Wei [1 ]
Li, Xia-fen [1 ]
Liu, Yi-chen [1 ]
Feng, Gai-li [1 ]
Tan, Hongwei [1 ]
Zhang, Yuan [1 ,2 ]
Xing, Guo-wen [1 ]
机构：
[1] Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China
[2] Beijing Normal Univ, Coll Chem, Key Lab Energy Convers & Storage Mat, Beijing 100875, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 68期
基金：
中国国家自然科学基金;
关键词：
PROBE; DNA;
D O I：
10.1039/d3cc02788k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.
引用
收藏
页码：10287 / 10290
页数：4
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