Emerging applications of extracellular vesicles in tumor therapy

被引：3
|
作者：
Luo, Hui [1 ,2 ]
Jin, Jing [3 ]
Jin, Jiajia [4 ]
Lou, Kecheng [1 ,2 ]
He, Hailan [1 ,2 ]
Feng, Shangzhi [1 ,2 ]
Zeng, Fei [1 ]
Zou, Junrong [2 ]
机构：
[1] Gannan Med Univ, Clin Coll 1, Ganzhou, Jiangxi, Peoples R China
[2] Gannan Med Univ, Affiliated Hosp 1, Dept Urol, Ganzhou, Jiangxi, Peoples R China
[3] Dongyang Maternal & Child Hlth Hosp, Dept Gynecol, Jinhua, Zhejiang, Peoples R China
[4] Dongyang Weishan Town Cent Hlth Hosp, Jinhua, Zhejiang, Peoples R China
来源：
CANCER NANOTECHNOLOGY | 2023年 / 14卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Extracellular vesicles; Exosomes; Nanotechnology; Drug delivery; Tumor therapy; MESENCHYMAL STEM-CELLS; MACROPHAGE-DERIVED EXOSOMES; DRUG-DELIVERY-SYSTEMS; IN-VITRO; BREAST-CANCER; STROMAL CELLS; BONE-MARROW; PLANT; PACLITAXEL; INHIBIT;
D O I：
10.1186/s12645-023-00217-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological characteristics distinguish them as unique carriers with specific pharmacokinetic, circulating metabolic, and biodistribution patterns in the delivery of therapeutic cargoes. They are critical mediators in the pathology of many diseases, including inflammatory diseases, fibrosis, and cancer, but they are also essential mediators in immunomodulation, cancer treatment, infectious defense, and tissue repair. In this review, we emphasize recent advances in oncology therapy using macrophage EVs, mesenchymal stem cell EVs, milk EVs, and plant EVs, as well as the advantages of EVs as delivery platforms and their prospective clinical applications and use.
引用
收藏
页数：25
相关论文
共 50 条
  • [1] Emerging applications of extracellular vesicles in tumor therapy
    Hui Luo
    Jing Jin
    Jiajia Jin
    Kecheng Lou
    Hailan He
    Shangzhi Feng
    Fei Zeng
    Junrong Zou
    Cancer Nanotechnology, 2023, 14
  • [2] Extracellular vesicles as emerging players in tumor biology
    Costa-Silva, Bruno
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2019, 49 : 38 - 38
  • [3] Exploiting sound for emerging applications of extracellular vesicles
    Zhuhao Wu
    Hongwei Cai
    Chunhui Tian
    Zheng Ao
    Lei Jiang
    Feng Guo
    Nano Research, 2024, 17 : 462 - 475
  • [4] Exploiting sound for emerging applications of extracellular vesicles
    Wu, Zhuhao
    Cai, Hongwei
    Tian, Chunhui
    Ao, Zheng
    Jiang, Lei
    Guo, Feng
    NANO RESEARCH, 2024, 17 (02) : 462 - 475
  • [5] Extracellular Vesicles: An Emerging Nanoplatform for Cancer Therapy
    Ma, Yifan
    Dong, Shiyan
    Li, Xuefeng
    Kim, Betty Y. S.
    Yang, Zhaogang
    Jiang, Wen
    FRONTIERS IN ONCOLOGY, 2021, 10
  • [6] Extracellular vesicles: emerging targets for cancer therapy
    Vader, Pieter
    Breakefield, Xandra O.
    Wood, Matthew J. A.
    TRENDS IN MOLECULAR MEDICINE, 2014, 20 (07) : 385 - 393
  • [7] Bacterial extracellular vesicles: Emerging nanoplatforms for biomedical applications
    Gurunathan, Sangiliyandi
    Kim, Jin-Hoi
    MICROBIAL PATHOGENESIS, 2023, 183
  • [8] Extracellular Vesicles and Their Applications in Tumor Diagnostics and Immunotherapy
    Strum, Scott
    Evdokimova, Valentina
    Radvanyi, Laszlo
    Spreafico, Anna
    CELLS, 2024, 13 (23)
  • [9] Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
    Tan, Mingdian
    Ge, Yizhi
    Wang, Xiaogang
    Wang, Yan
    Liu, Yi
    He, Feng
    Teng, Hongqi
    TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 2023, 22
  • [10] The Role of Extracellular Vesicles in Tumor Therapy and Imaging
    Feng, Ting
    Wan, Yilin
    Cui, Shengsheng
    Liu, Yanlei
    ADVANCED THERAPEUTICS, 2023, 6 (12)
12345