Adaptations to clinical trials in health research: a guide for clinical researchers

被引:3
作者
Holliday, Elizabeth G. [1 ]
Weaver, Natasha [1 ]
Barker, Daniel [1 ]
Oldmeadow, Christopher [1 ,2 ]
机构
[1] Univ Newcastle, Newcastle, NSW, Australia
[2] Hunter Med Res Inst, Newcastle, NSW, Australia
关键词
Clinical trials as topic; Biostatistics; SAMPLE-SIZE; DESIGN;
D O I
10.5694/mja2.51936
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:451 / 454
页数:4
相关论文
共 8 条
[1]   Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs [J].
Burnett, Thomas ;
Mozgunov, Pavel ;
Pallmann, Philip ;
Villar, Sofia S. ;
Wheeler, Graham M. ;
Jaki, Thomas .
BMC MEDICINE, 2020, 18 (01)
[2]   Sample size re-estimation: recent developments and practical considerations [J].
Gould, AL .
STATISTICS IN MEDICINE, 2001, 20 (17-18) :2625-2643
[3]   Maximum inflation of the type 1 error rate when sample size and allocation rate are adapted in a pre-planned interim look [J].
Graf, Alexandra C. ;
Bauer, Peter .
STATISTICS IN MEDICINE, 2011, 30 (14) :1637-1647
[4]   Adaptive sample size calculations in group sequential trials [J].
Lehmacher, W ;
Wassmer, G .
BIOMETRICS, 1999, 55 (04) :1286-1290
[5]   Adaptive increase in sample size when interim results are promising: A practical guide with examples [J].
Mehta, Cyrus R. ;
Pocock, Stuart J. .
STATISTICS IN MEDICINE, 2011, 30 (28) :3267-3284
[6]   Adaptive designs in clinical trials: why use them, and how to run and report them [J].
Pallmann, Philip ;
Bedding, Alun W. ;
Choodari-Oskooei, Babak ;
Dimairo, Munyaradzi ;
Flight, Laura ;
Hampson, Lisa V. ;
Holmes, Jane ;
Mander, Adrian P. ;
Odondi, Lang'O ;
Sydes, Matthew R. ;
Villar, Sofia S. ;
Wason, James M. S. ;
Weir, Christopher J. ;
Wheeler, Graham M. ;
Yap, Christina ;
Jaki, Thomas .
BMC MEDICINE, 2018, 16
[7]   Practical characteristics of adaptive design in phase 2 and 3 clinical trials [J].
Sato, A. ;
Shimura, M. ;
Gosho, M. .
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2018, 43 (02) :170-180
[8]   Optimal design of multi-arm multi-stage trials [J].
Wason, James M. S. ;
Jaki, Thomas .
STATISTICS IN MEDICINE, 2012, 31 (30) :4269-4279