Phenothiazine-based multifunctional fluorescent probe for one-site rapid detection of hydrazine in cells, soil, water samples and test strip

被引：16
作者：
Huang, Yongfei [1 ,2 ]
Liang, Junping [1 ,2 ]
Fan, Zhefeng [1 ,2 ]
机构：
[1] Shanxi Normal Univ, Key Lab Magnet Mol & Magnet Informat Mat, Minist Educ, Taiyuan 030032, Peoples R China
[2] Shanxi Normal Univ, Sch Chem & Mat Sci, Taiyuan 030032, Peoples R China
来源：
DYES AND PIGMENTS | 2023年 / 213卷
关键词：
Fluorescent probe; Hydrazine; Cell imaging; Actual sample; Test strip; SPECTROPHOTOMETRIC DETERMINATION; RATIOMETRIC PROBE; AQUEOUS-SOLUTION; NAKED-EYE; GAS STATE; CYCLIZATION; MECHANISM; SENSOR;
D O I：
10.1016/j.dyepig.2023.111164
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Hydrazine is widely used as a wide range of industrial chemical reagents. Because of its toxicity and explo-siveness, it poses a serious threat to human health and ecological security. Therefore, it is of great significance to develop a real-time tracing method for hydrazine. Here, a novel turn-on fluorescent probe SXNU-1 for the detection of hydrazine was synthesized based on phenothiazine. SXNU-1 showed excellent selectivity toward hydrazine over various competitive species. Vinyl group with cyano and ethylacetate groups in SXNU-1 could react with hydrazine to form Schiff's base, showing bright green fluorescence. The response mechanism was verified by theoretical calculation, 1H NMR titration and HRMS. In addition, SXNU-1 can determine hydrazine in soil, water samples and test strip. Because SXNU-1 has good cell membrane permeability, it can monitor different concentrations of hydrazine in HeLa cells. Therefore, we believe that SXNU-1 has great potential in the analysis and monitoring of environmental pollutants.
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页数：8
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