Dosimetric evaluation of VMAT automated breast treatment plans: Towards the establishment of an institutional plan acceptability criteria

被引:0
作者
Acquah, George Felix [1 ,2 ]
Hasford, Francis [2 ,3 ]
Tagoe, Samuel Nii Adu [2 ,4 ]
Diakite, Adama [5 ]
Adjenou, Victor [6 ]
Osei, Ernest [7 ,8 ]
机构
[1] Ctr Int Cancerol Lome, Med Physcis Dept, Lome, Togo
[2] Univ Ghana, Grad Sch Nucl & Allied Sci, Dept Med Phys, Legon, Ghana
[3] Ghana Atom Energy Commiss, Radiol & Med Sci Res Inst, Accra, Ghana
[4] Korle Bu Teaching Hosp, Natl Radiotherapy Oncol & Nucl Med Ctr, Med Phys, Accra, Ghana
[5] Ctr Int Cancerol Lome, Radiat Oncol Dept, Lome, Togo
[6] Univ Lome, Campus Teaching Hosp, Radiol Dept, Lome, Togo
[7] Grand River Reg Canc Ctr, Med Phys Dept, Kitchener, ON, Canada
[8] Univ Waterloo, Dept Phys & Astron, Waterloo, ON, Canada
关键词
dosimetric indices; breast radiotherapy; plan quality; VMAT plan; acceptability criteria; CONTRALATERAL BREAST; RADIATION-THERAPY; RADIOTHERAPY; CANCER; RISK; PREDICTION; QUALITY;
D O I
10.2478/pjmpe-2023-0020
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Introduction: To evaluate the clinical suitability of the current facility-based treatment plan protocol in establishing acceptability criteria.Material and methods: Automated Volumetric Arc Therapy (VMAT) treatment plans were retrospectively evaluated for intact breast and chest-wall cancer patients from January 2021 to January 2023.Results: A total of 94 patients were planned and treated using automated contouring and VMAT planning technique. The number of patients planned and treated for intact breast and chest-wall were 41 (43.6%) and 53 (56.4%), respectively. The mean intact breast volumes for optimization (Brst_opt) receiving 95% and 105% of the prescribed doses were 92.80% +/- 1.11 and 1.54% +/- 1.02, respectively. Their corresponding mean chest-wall volumes for optimization (Chst_opt) were 90.65% +/- 3.19 and 2.28% +/- 2.99, respectively. For left-sided cases, the mean heart dose received was 4.61 Gy +/- 1.76 and 5.18 Gy +/- 1.55 for intact breast plans and that for chest-wall plans, respectively. The mean ipsilateral lung volume receiving 20 Gy of the prescribed dose was 12.22% +/- 3.86 and 13.19% +/- 3.74 for intact breast plans and chest-wall plans, respectively. For the Brst_opt and Chst_opt dose metrics were calculated; the mean homogeneity index (HI) was 0.14 +/- 0.03 and 0.15 +/- 0.04, mean uniformity index (UI) was 1.09 +/- 0.03 and 1.11 +/- 0.03, and mean conformity index (CI) were 0.92 +/- 0.04 and 0.91 +/- 0.04, respectively.Conclusions: The dosimetric evaluation shows a good dose distribution in the target volumes with minimal doses to the organs at risk (OAR). Assessment of the current data affirms the clinical usefulness of the facility-adopted protocol in achieving quality treatment plans for intact breast and chest-wall irradiations. The establishment of plan acceptability criteria will help achieve improved overall treatment outcomes.
引用
收藏
页码:185 / 194
页数:10
相关论文
共 22 条
[1]   Overview of breast cancer external beam radiation therapy in Ghana: Towards the establishment of a national standardized treatment guidelines for improved patient care [J].
Acquah, George Felix ;
Hasford, Francis ;
Tagoe, Samuel ;
Kyere, Augustine ;
Owusu-Kyere, Reynolds ;
Kyeremeh, Philip Oppong ;
Aznar, Marianne C. ;
Osei, Ernest .
SCIENTIFIC AFRICAN, 2022, 17
[2]  
Adnani N, 2020, INT J RADIAT ONCOL, V108, pE46
[3]   Radiation therapy for breast cancer: Literature review [J].
Balaji, Karunakaran ;
Subramanian, Balaji ;
Yadav, Poonam ;
Radha, Chandrasekaran Anu ;
Ramasubramanian, Velayudham .
MEDICAL DOSIMETRY, 2016, 41 (03) :253-257
[4]   CANCER IN THE CONTRALATERAL BREAST AFTER RADIOTHERAPY FOR BREAST-CANCER [J].
BOICE, JD ;
HARVEY, EB ;
BLETTNER, M ;
STOVALL, M ;
FLANNERY, JT .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (12) :781-785
[5]   CAUSE-SPECIFIC MORTALITY IN LONG-TERM SURVIVORS OF BREAST-CANCER WHO PARTICIPATED IN TRIALS OF RADIOTHERAPY [J].
CUZICK, J ;
STEWART, H ;
RUTQVIST, L ;
HOUGHTON, J ;
EDWARDS, R ;
REDMOND, C ;
PETO, R ;
BAUM, M ;
FISHER, B ;
HOST, H ;
LYTHGOE, J ;
RIBEIRO, G ;
SCHEURLEN, H .
JOURNAL OF CLINICAL ONCOLOGY, 1994, 12 (03) :447-453
[6]   Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer [J].
Darby, Sarah C. ;
Ewertz, Marianne ;
McGale, Paul ;
Bennet, Anna M. ;
Blom-Goldman, Ulla ;
Bronnum, Dorthe ;
Correa, Candace ;
Cutter, David ;
Gagliardi, Giovanna ;
Gigante, Bruna ;
Jensen, Maj-Britt ;
Nisbet, Andrew ;
Peto, Richard ;
Rahimi, Kazem ;
Taylor, Carolyn ;
Hall, Per .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (11) :987-998
[7]   Automatic treatment planning based on three-dimensional dose distribution predicted from deep learning technique [J].
Fan, Jiawei ;
Wang, Jiazhou ;
Chen, Zhi ;
Hu, Chaosu ;
Zhang, Zhen ;
Hu, Weigang .
MEDICAL PHYSICS, 2019, 46 (01) :370-381
[8]  
Ferlay J, 2010, BREAST CANCER EPIDEMIOLOGY, P1, DOI 10.1007/978-1-4419-0685-4_1
[9]  
Gregoire V, 2010, J ICRU, V10, P1
[10]   Radiation-induced second cancers: The impact of 3D-CRT and IMRT [J].
Hall, EJ ;
Wuu, CS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 56 (01) :83-88