Exploring Interactions and Properties of the Sodium Carboxymethyl Cellulose-Chitosan Biopolymer Complex

The complex of sodium carboxymethyl cellulose (CMC) and chitosan (CH) in aqueous solution can be used for biomedical applications and is very beneficial for tissue engineering, drug delivery, and disease treatment. This article presents elaboration and properties of the complex of two polysaccharides with opposite charges of CMC/CH in aqueous solutions. The electrical conductivity under the influence of increasing concentrations of the CMC/CH mixtures from (0.5 to 10) g l-1 and increasing temperatures from 288.15 to 318.15 K is investigated. The reduced conductivities, sigma red$\left(\sigma\right)_{\text{red}}$, energy of activation Delta E sigma$\Delta E_{\sigma}$, the Gibbs free energy of conductivity Delta G sigma red$\Delta G_{\text{& amp;amp;amp;amp;amp;sigma;red}}$, and the activations parameters of the enthalpy (Delta Hred$\Delta H_{\text{red}}$) and entropy (Delta Sred$\Delta S_{\text{red}}$) are estimated. This work opens up new possibilities for biopolymer complexes and emphasizes the importance of two polysaccharides with different charges. The interaction between a complex of carboxymethyl cellulose and chitosan forms the basis for various applications in areas such as drug delivery, biomedical engineering, food science, and more, utilizing their unique properties and ability to interact based on their different charges.image (c) 2024 WILEY-VCH GmbH