Impact of the new ultra-high sensitivity mode in a long axial field-of-view PET/CT

被引：30
作者：
Mingels, Clemens [1 ]
Weidner, Sabine [1 ]
Sari, Hasan [1 ,2 ]
Buesser, Dorothee [1 ]
Zeimpekis, Konstantinos [1 ]
Shi, Kuangyu [1 ]
Alberts, Ian [1 ]
Rominger, Axel [1 ]
机构：
[1] Univ Bern, Bern Univ Hosp, Inselspital, Dept Nucl Med, Freiburgstr 18, CH-3010 Bern, Switzerland
[2] Siemens Healthcare AG, Adv Clin Imaging Technol, Lausanne, Switzerland
来源：
ANNALS OF NUCLEAR MEDICINE | 2023年 / 37卷 / 05期
关键词：
Whole-body PET; CT; LAFOV PET; Ultra-high sensitivity; High sensitivity; Acquisition time; SCANNER;
D O I：
10.1007/s12149-023-01827-y
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
ObjectiveLong axial field-of-view (LAFOV) PET/CT showed improved performance resulting from higher sensitivity. The aim was to quantify the impact of using the full acceptance angle (UHS) in image reconstructions with the Biograph Vision Quadra LAFOV PET/CT (Siemens Healthineers) compared to the limited acceptance angle (high sensitivity mode, HS).Methods38 oncological patients examined on a LAFOV Biograph Vision Quadra PET/CT were analysed. 15 patients underwent [F-18]FDG-PET/CT, 15 patients underwent [F-18]PSMA-1007 PET/CT, and 8 patients underwent [Ga-68]Ga-DOTA-TOC PET/CT. Signal-to-noise ratio (SNR) and standardised uptake values (SUVmean/max/peak) were used to compare UHS and HS with different acquisition times.ResultsThe SNR was significantly higher for UHS compared to HS over all acquisition times (SNR UHS/HS [F-18]FDG: 1.35 +/- 0.02, p < 0.001; [F-18]PSMA-1007: 1.25 +/- 0.02, p < 0.001; [Ga-68]Ga-DOTA-TOC: 1.29 +/- 0.02, p < 0.001).ConclusionUHS showed significantly higher SNR opening the possibility of halving short acquisition times. This is of advantage in further reduction of whole-body PET/CT acquisition.
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收藏
页码：310 / 315
页数：6
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