History of trauma is a critical treatment target for individuals at clinical high-risk for psychosis

被引:3
作者
Zarubin, Vanessa C. C. [1 ,2 ]
Gupta, Tina [3 ]
Mittal, Vijay A. A. [1 ,2 ,4 ,5 ,6 ]
机构
[1] Northwestern Univ, Dept Psychol, Evanston, IL 60208 USA
[2] Northwestern Univ, Inst Innovat Dev Sci DevSci, Chicago, IL 60208 USA
[3] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
[4] Northwestern Univ, Dept Psychiat, Chicago, IL USA
[5] Northwestern Univ, Med Social Sci, Chicago, IL USA
[6] Northwestern Univ, Inst Policy Res IPR, Chicago, IL USA
来源
FRONTIERS IN PSYCHIATRY | 2023年 / 13卷
关键词
clinical high-risk (CHR) for psychosis; trauma; treatment development; childhood trauma and adversity; psychosis; FOCUSED TREATMENT; STRESS; MODEL; VULNERABILITY; SYMPTOMS; HEALTH; EXPERIENCES; ADOLESCENTS; OUTCOMES; THERAPY;
D O I
10.3389/fpsyt.2022.1102464
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
People meeting criteria for a clinical high-risk (CHR) for psychosis syndrome frequently represent a heterogeneous, help-seeking, and dynamic population. Among the numerous symptoms and risk factors for psychosis, exposure to trauma stands out as both highly prevalent and poorly understood. Indeed, while up to 80% of individuals meeting criteria for a CHR syndrome report trauma histories, there is currently limited research dedicated to this specific area. This is particularly problematic as trauma is tied to risk for conversion, leads to a range of clinical issues, and contributes to disability and poor quality of life. Fortunately, recent research in the general population has led to a significant evolution in the way trauma is assessed and understood, and further, some studies have indicated that targeted trauma interventions in formal psychotic disorders are highly effective. However, direct adoption is challenging as the CHR syndrome holds a number of unique concerns (e.g., clinical heterogeneity, developmental trauma), and characteristically, involves a developing pediatric or young adult population that also comes with specific considerations (e.g., living with caregivers, transitionary period in roles). In this "perspective" we frame the issues around understanding trauma in CHR individuals, discuss viable treatments and unique considerations, and provide suggestions for future steps in developing and incorporating trauma-focused interventions in this population.
引用
收藏
页数:7
相关论文
共 60 条
[1]   Cognitive behavioural social skills training: Methods of a randomized controlled trial for youth at risk of psychosis [J].
Addington, Jean ;
Liu, Lu ;
Santesteban-Echarri, Olga ;
Brummitt, Kali ;
Braun, Amy ;
Cadenhead, Kristin S. ;
Cornblatt, Barbara A. ;
Holden, Jason L. ;
Granholm, Eric .
EARLY INTERVENTION IN PSYCHIATRY, 2021, 15 (06) :1626-1636
[2]   A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis [J].
Addington, Jean ;
Epstein, Irvin ;
Liu, Lu ;
French, Paul ;
Boydell, Katherine M. ;
Zipursky, Robert B. .
SCHIZOPHRENIA RESEARCH, 2011, 125 (01) :54-61
[3]   The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis [J].
Amminger, G. Paul ;
Nelson, Barnaby ;
Markulev, Connie ;
Yuen, Hok Pan ;
Schafer, Miriam R. ;
Berger, Maximus ;
Mossaheb, Nilufar ;
Schloegelhofer, Monika ;
Smesny, Stephan ;
Hickie, Ian B. ;
Berger, Gregor E. ;
Chen, Eric Y. H. ;
de Haan, Lieuwe ;
Nieman, Dorien H. ;
Nordentoft, Merete ;
Riecher-Roessler, Anita ;
Verma, Swapna ;
Thompson, Andrew ;
Yung, Alison Ruth ;
McGorry, Patrick D. .
BIOLOGICAL PSYCHIATRY, 2020, 87 (03) :243-252
[4]   Trauma-focused imaginal exposure for auditory hallucinations: A case series [J].
Brand, Rachel M. ;
Bendall, Sarah ;
Hardy, Amy ;
Rossell, Susan L. ;
Thomas, Neil .
PSYCHOLOGY AND PSYCHOTHERAPY-THEORY RESEARCH AND PRACTICE, 2021, 94 :408-425
[5]   Complex Trauma in Adolescents and Adults Effects and Treatment [J].
Briere, John ;
Scott, Catherine .
PSYCHIATRIC CLINICS OF NORTH AMERICA, 2015, 38 (03) :515-+
[6]   Reductions in reported persecutory ideation and psychotic-like experiences during exposure therapy for posttraumatic stress disorder [J].
Buck, Benjamin ;
Norr, Aaron ;
Katz, Andrea ;
Gahm, Gregory A. ;
Reger, Greg M. .
PSYCHIATRY RESEARCH, 2019, 272 :190-195
[7]   An Individualized Risk Calculator for Research in Prodromal Psychosis [J].
Cannon, Tyrone D. ;
Yu, Changhong ;
Addington, Jean ;
Bearden, Carrie E. ;
Cadenhead, Kristin S. ;
Cornblatt, Barbara A. ;
Heinssen, Robert ;
Jeffries, Clark D. ;
Mathalon, Daniel H. ;
McGlashan, Thomas H. ;
Perkins, Diana O. ;
Seidman, Larry J. ;
Tsuang, Ming T. ;
Walker, Elaine F. ;
Woods, Scott W. ;
Kattan, Michael W. .
AMERICAN JOURNAL OF PSYCHIATRY, 2016, 173 (10) :980-988
[8]   Cannabidiol (CBD) as a novel treatment in the early phases of psychosis [J].
Chesney, Edward ;
Oliver, Dominic ;
McGuire, Philip .
PSYCHOPHARMACOLOGY, 2022, 239 (05) :1179-1190
[9]   Motor Clusters Reveal Differences in Risk for Psychosis, Cognitive Functioning, and Thalamocortical Connectivity: Evidence for Vulnerability Subtypes [J].
Dean, Derek J. ;
Walther, Sebastian ;
Bernard, Jessica A. ;
Mittal, Vijay A. .
CLINICAL PSYCHOLOGICAL SCIENCE, 2018, 6 (05) :721-734
[10]   Hippocampal Shape Abnormalities Predict Symptom Progression in Neuroleptic-Free Youth at Ultrahigh Risk for Psychosis [J].
Dean, Derek J. ;
Orr, Joseph M. ;
Bernard, Jessica A. ;
Gupta, Tina ;
Pelletier-Baldelli, Andrea ;
Carol, Emily E. ;
Mittal, Vijay A. .
SCHIZOPHRENIA BULLETIN, 2016, 42 (01) :161-169