Beyond the Lungs-Emerging Challenges in Adult Cystic Fibrosis Care

被引：5

作者：

Mulrennan, Siobhain ^{[1
]}

Sapru, Karuna ^{[2
]}

Tewkesbury, Daniel ^{[2
]}

Jones, Andrew M. ^{[2
,3
]}

机构：

[1] Sir Charles Gairdner Hosp, Perth, Australia

[2] Wythenshawe Hosp, Manchester Adult Cyst Fibrosis Ctr, Manchester, England

[3] Wythenshawe Hosp, Manchester Adult Cyst Fibrosis Ctr, Southmoor Rd, Manchester M23 9LT, England

来源：

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE | 2023年 / 44卷 / 02期

关键词：

cystic fibrosis; CFTR modulators; aging; malignancy; cardiovascular disease; bone health; RISK-FACTORS; VERTEBRAL FRACTURES; LIVER-DISEASE; DEPRESSION; PREGNANCY; HEALTH; WOMEN; PREVALENCE; CFTR; ASSOCIATION;

D O I：

10.1055/s-0042-1758734

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Cystic fibrosis (CF) is a multisystem disease. This article provides an up-to-date review of many of the nonrespiratory complications of CF, including mental health issues, nutritional and gastrointestinal problems, fertility issues, diabetes mellitus, bone health and musculoskeletal problems, liver disease, renal problems, and risk of malignancy. It highlights the recent impact of new therapies, including CF transmembrane conductance regulator modulators, on the nonrespiratory complications of CF and provides insights into the potential challenges faced by an aging population of adults with CF and their caregivers, including the potential future risk for cardiovascular disease.

引用

收藏

页码：307 / 313

页数：7

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