Epidermal Wearable Biosensors for the Continuous Monitoring of Biomarkers of Chronic Disease in Interstitial Fluid

被引:15
作者
Yuan, Xichen [1 ,2 ,3 ]
Ouaskioud, Oumaima [1 ,3 ]
Yin, Xu [2 ]
Li, Chen [1 ,3 ]
Ma, Pengyi [1 ,3 ]
Yang, Yang [4 ]
Yang, Peng-Fei [1 ,3 ]
Xie, Li [3 ]
Ren, Li [1 ,3 ]
机构
[1] Northwestern Polytech Univ, Key Lab Flexible Elect Zhejiang Prov, Ningbo Inst, Ningbo 315103, Peoples R China
[2] Northwestern Polytech Univ, Sch Mech Engn, MOE Key Lab Micro & Nano Syst Aerosp, Xian 710072, Peoples R China
[3] Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Xian 710072, Peoples R China
[4] Chongqing Univ, Key Lab Low Grade Energy Utilizat Technol & Syst, Minist Educ, Chongqing 400030, Peoples R China
基金
中国国家自然科学基金;
关键词
interstitial fluid; epidermis; wearable biosensor; chronic disease; TRANSDERMAL REVERSE IONTOPHORESIS; SALIVARY URIC-ACID; IN-VIVO; GLUCOWATCH(R) BIOGRAPHER; MOUTHGUARD BIOSENSOR; BLOOD-GLUCOSE; HUMAN SKIN; MICRODIALYSIS; EXTRACTION; DRUG;
D O I
10.3390/mi14071452
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Healthcare technology has allowed individuals to monitor and track various physiological and biological parameters. With the growing trend of the use of the internet of things and big data, wearable biosensors have shown great potential in gaining access to the human body, and providing additional functionality to analyze physiological and biochemical information, which has led to a better personalized and more efficient healthcare. In this review, we summarize the biomarkers in interstitial fluid, introduce and explain the extraction methods for interstitial fluid, and discuss the application of epidermal wearable biosensors for the continuous monitoring of markers in clinical biology. In addition, the current needs, development prospects and challenges are briefly discussed.
引用
收藏
页数:24
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