US LI-RADS in surveillance for recurrent hepatocellular carcinoma after curative treatment

被引：3

作者：

Huang, Hui ^{[1
]}

Cheng, Mei-Qing ^{[1
]}

He, Dan-Ni ^{[1
,2
]}

Xian, Meng-Fei ^{[1
]}

Zeng, Dan ^{[1
]}

Wu, Shao-Hong ^{[1
]}

Li, Chao-Qun ^{[1
,3
]}

Ruan, Si-Min ^{[1
]}

Li, Ming-De ^{[1
]}

Lin, Man-Xia ^{[1
]}

Lu, Ming-De ^{[1
,4
]}

Kuang, Ming ^{[1
,4
]}

Wang, Wei ^{[1
]}

Chen, Li-Da ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Affiliated Hosp 1, Inst Diagnost & Intervent Ultrasound, Dept Med Ultrason,Ultrasom Artificial Intelligenc, 58 Zhongshan Rd 2, Guangzhou 510080, Peoples R China

[2] Sun Yat Sen Univ, Affiliated Hosp 7, Dept Med Ultrason, Shenzhen, Peoples R China

[3] Sichuan Univ, Dept Ultrasound Med, West China Xiamen Hosp, Xiamen, Peoples R China

[4] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Guangzhou, Peoples R China

来源：

EUROPEAN RADIOLOGY | 2023年 / 33卷 / 12期

基金：

中国国家自然科学基金;

关键词：

Hepatocellular carcinoma; Recurrence; Surveillance; Ultrasound; CLINICAL-PRACTICE GUIDELINES; ATTENTION NETWORK; PREDICTION METHOD; MANAGEMENT; ULTRASOUND; DIAGNOSIS; ACCURACY; CRITERIA; NODULES; UPDATE;

D O I：

10.1007/s00330-023-09903-7

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

ObjectivesTo investigate the performance of US LI-RADS in surveillance for recurrent hepatocellular carcinoma (RHCC) after curative treatment.Materials and methodsThis study enrolled 644 patients between January 2018 and August 2018 as a derivation cohort, and 397 patients from September 2018 to December 2018 as a validation cohort. The US surveillance after HCC curative treatment was performed. The US LI-RADS observation categories and visualization scores were analyzed. Four criteria using US LI-RADS or Alpha-fetoprotein (AFP) as the surveillance algorithm were evaluated. The sensitivity, specificity, and negative predictive value (NPV) were calculated.ResultsA total of 212 (32.9%) patients in derivation cohort and 158 (39.8%) patients in validation cohort were detected to have RHCCs. The criterion of US-2/3 or AFP & GE; 20 & mu;g/L had higher sensitivity (derivation, 96.7% vs 92.9% vs 81.1% vs 90.6%; validation, 96.2% vs 90.5% vs 80.4% vs 89.9%) and NPV (derivation, 95.7% vs 93.3% vs 88.0% vs 91.8%; validation, 94.6% vs 89.4% vs 83.6% vs 89.0%), but lower specificity (derivation, 35.9% vs 48.2% vs 67.6% vs 51.9%; validation, 43.5% vs 52.7% vs 66.1% vs 54.0%) than criterion of US-2/3, US-3, and US-3 or AFP & GE; 20 & mu;g/L. Analysis of the visualization score subgroups confirmed that the sensitivity (89.2-97.6% vs 81.0-83.3%) and NPV(88.4-98.0% vs 80.0-83.3%) of score A and score B groups were higher than score C group in criterion of US-2/3 in both two cohorts.ConclusionsIn the surveillance for RHCC, US LI-RADS with AFP had a high sensitivity and NPV when US-2/3 or AFP & GE; 20 & mu;g/L was considered a criterion.

引用

页码：9357 / 9367

页数：11