Palladium-catalyzed coupling of amides and cyclopropanols for the synthesis of γ-diketones

被引：4

作者：

Fang, Lili ^{[1
]}

Jia, Shuqi ^{[1
]}

Fan, Shuaixin ^{[1
]}

Zhu, Jin ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210023, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 69期

基金：

中国国家自然科学基金;

关键词：

ACTIVATION; NICKEL; REAGENTS;

D O I：

10.1039/d3cc02888g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium catalytic method has been developed for the coupling of amides and cyclopropanols to gamma-diketones, through simultaneous C-N and C-C activation. Heteroatom ligand exchange and heteroatom-to-carbon ligation mode switching enable the achievement of molecular cross-coupling in an amide N-atom structural context-dependent manner, avoiding any stoichiometric organometallic reagent or base.

引用

页码：10392 / 10395

页数：4

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