In vitro cytotoxicity, corrosion and antibacterial efficiencies of Zn doped hydroxyapatite coated Ti based implant materials

被引：20

作者：

Buyuksungur, Senem ^{[1
]}

Huri, Pinar Yilgor ^{[2
]}

Schmidt, Juergen ^{[3
]}

Pana, Iulian ^{[4
]}

Dinu, Mihaela ^{[4
]}

Vitelaru, Catalin ^{[4
]}

Kiss, Adrian E. ^{[4
]}

Tamay, Dilara Goksu ^{[1
,5
]}

Hasirci, Vasif ^{[1
,5
,6
,7
]}

Vladescu, Alina ^{[4
,8
,11
]}

Hasirci, Nesrin ^{[1
,5
,9
,10
,12
]}

机构：

[1] Middle East Tech Univ METU, Ctr Excellence Biomat & Tissue Engn, BIOMATEN, TR-06800 Ankara, Turkiye

[2] Ankara Univ, Dept Biomed Engn, TR-06830 Ankara, Turkiye

[3] INNOVENT eV Technologieentwicklung, Gruppenleiter Elektrochem, Prussingstr 27, D-07745 Jena, Germany

[4] Natl Inst Res & Dev Optoelect INOE 2000, 409 Atomistilor Str, Magurele 077125, Romania

[5] METU, Dept Biomed Engn, TR-06800 Ankara, Turkiye

[6] Acibadem Mehmet Ali Aydinlar Univ, Biomed Engn Dept, TR-34684 Istanbul, Turkiye

[7] Acibadem Mehmet Ali Aydinlar Univ, Biomat Ctr, TR-34684 Istanbul, Turkiye

[8] Natl Res Tomsk Polytech Univ, Res Ctr Phys Mat Sci & Composite Mat, Lenin Ave 43, Tomsk 634050, Russia

[9] Middle East Tech Univ, Dept Chem, TR-06800 Ankara, Turkiye

[10] Near East Univ, Tissue Engn & Biomat Res Ctr, Mersin 10, TR-99138 Nistcosia, Turkiye

[11] Natl Inst R&D Optoelect, Magurele, Romania

[12] Near East Univ NEU, Nistcosia, Turkiye

来源：

CERAMICS INTERNATIONAL | 2023年 / 49卷 / 08期

关键词：

Film; Interfaces; Corrosion; Apatite; Biomedical applications; SURFACE FREE-ENERGY; VIVO BIOCOMPATIBILITY; ZINC; DEPOSITION; SCAFFOLDS; COATINGS; FILMS; AG;

D O I：

10.1016/j.ceramint.2022.12.119

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Ti6Al4V alloy is successfully used as implant material in dental and orthopedic surgeries for years due to its much better compatibility, lower density, corrosion resistance, etc. compared to the other metals. Meantime, modification of the surface of these alloys is needed to enhance material-tissue interaction and osteointegration between the implant and the bone. In this study, Ti6Al4V alloy surfaces were modified by application of RF magnetron sputtering technique and coated with zinc (Zn) doped hydroxyapatite (HAp). The obtained coating was very stable with highly crystalline structure, demonstrated enhanced corrosion resistance, osteointegration and antimicrobial effectiveness against Escherichia coli (E. coli) bacteria.

引用

页码：12570 / 12584

页数：15

共 67 条

[1] Cytotoxicity of zinc-containing bioactive glasses in contact with human osteoblasts [J].

Aina, Valentina ;

Perardi, Alessandra ;

Bergandi, Loredana ;

Malavasi, Gianluca ;

Menabue, Ledi ;

Morterra, Claudio ;

Ghigo, Dario .

CHEMICO-BIOLOGICAL INTERACTIONS, 2007, 167 (03) :207-218

[2] The Improvement in Surface Properties of Metallic Implant via Magnetron Sputtering: Recent Progress and Remaining Challenges [J].

Akhtar, Memoona ;

Uzair, Syed Ahmed ;

Rizwan, Muhammad ;

Ur Rehman, Muhammad Atiq .

FRONTIERS IN MATERIALS, 2022, 8

[3] Prevalence characteristics, and impacts of work-related musculoskeletal disorders: a survey among physical therapists in the State of Kuwait [J].

Alrowayeh, Hesham N. ;

Alshatti, Talal A. ;

Aljadi, Sameera H. ;

Fares, Majda ;

Alshamire, Mishayek M. ;

Alwazan, Sahar S. .

BMC MUSCULOSKELETAL DISORDERS, 2010, 11

[4] Recent advances in magnetron sputtering [J].

Arnell, RD ;

Kelly, PJ .

SURFACE & COATINGS TECHNOLOGY, 1999, 112 (1-3) :170-176

[5]

Baboian R, 2005, ASTM INT MAN SER, P1, DOI 10.1520/MNL11005M

[6]

Baruwa A.D., 2021, J BIOTRIBOCORROS, V7, P7, DOI [10.1007/s40735, DOI 10.1007/S40735]

[7] 3D printed poly(ε-caprolactone) scaffolds modified with hydroxyapatite and poly(propylene fumarate) and their effects on the healing of rabbit femur defects [J].

Buyuksungur, Senem ;

Tanir, Tugba Endogan ;

Buyuksungur, Arda ;

Bektas, Ezgi Irem ;

Kose, Gamze Torun ;

Yucel, Deniz ;

Beyzadeoglu, Tahsin ;

Cetinkaya, Engin ;

Yenigun, Cagri ;

Tonuk, Ergin ;

Hasirci, Vasif ;

Hasirci, Nesrin .

BIOMATERIALS SCIENCE, 2017, 5 (10) :2144-2158

[8] Zinc Status Index (ZSI) for Quantification of Zinc Physiological Status [J].

Cheng, Jacquelyn ;

Bar, Haim ;

Tako, Elad .

NUTRIENTS, 2021, 13 (10)

[9] Evaluation of surface modification techniques on the ability of apatite formation and corrosion behavior in synthetic body fluid: An in vitro study [J].

Cotrut, Cosmin M. ;

Ionescu, Ionut C. ;

Ungureanu, Elena ;

Berbecaru, Andrei ;

Zamfir, Raluca I. ;

Vladescu, Alina ;

Vranceanu, Diana M. .

SURFACES AND INTERFACES, 2021, 22

[10] In vitro and in vivo biocompatibility of Mg-Zn-Ca alloy operative clip [J].

Ding, Pengfei ;

Liu, Yuanchao ;

He, Xianghui ;

Liu, Debao ;

Ghen, Minfang .

BIOACTIVE MATERIALS, 2019, 4 :236-244

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