Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery

被引:0
作者
Passias, Peter G. [1 ,2 ]
Williamson, Tyler K. [3 ]
Kummer, Nicholas A. [1 ,2 ]
Pellise, Ferran [4 ]
Lafage, Virginie [5 ]
Lafage, Renaud [6 ]
Serra-Burriel, Miguel [7 ]
Smith, Justin S. [8 ]
Line, Breton [9 ]
Vira, Shaleen [10 ]
Gum, Jeffrey L. [11 ]
Haddad, Sleiman [4 ]
Perez-Grueso, Francisco Javier Sanchez
Schoenfeld, Andrew J. [12 ]
Daniels, Alan H. [13 ]
Chou, Dean [14 ]
Klineberg, Eric O. [15 ]
Gupta, Munish C. [16 ]
Kebaish, Khaled M. [17 ]
Kelly, Michael P. [18 ]
Hart, Robert A. [19 ]
Burton, Douglas C. [20 ]
Kleinstuck, Frank
Obeid, Ibrahim [21 ]
Shaffrey, Christopher I. [22 ]
Alanay, Ahmet [23 ,24 ]
Ames, Christopher P. [14 ]
Schwab, Frank J. [5 ]
Hostin Jr, Richard A.
Bess, Shay [9 ]
Int Spine Study Grp [25 ]
机构
[1] NYU Langone Orthoped Hosp, New York Spine Inst, Dept Orthoped, New York, NY USA
[2] NYU Langone Orthoped Hosp, New York Spine Inst, Dept Neurol Surg, New York, NY USA
[3] Univ Texas Hlth San Antonio, Dept Orthopaed Surg, San Antonio, TX USA
[4] Vall dHebron Hosp, Spine Surg Unit, Barcelona, Spain
[5] Lenox Hill Hosp, Dept Orthopaed, New York, NY USA
[6] Hosp Special Surg, Dept Orthopaed, New York, NY USA
[7] Univ Pompeu Fabra, Ctr Res Hlth & Econ, Barcelona, Spain
[8] Univ Virginia, Med Ctr, Dept Neurosurg, Charlottesville, VA USA
[9] Presbyterian St Lukes Rocky Mt Hosp Children, Denver Int Spine Ctr, Presbyterian St, Denver, CO USA
[10] UT Southwestern Med Ctr, Dept Orthoped Surg, Dallas, TX USA
[11] Norton Leatherman Spine Ctr, Louisville, KY USA
[12] Hosp Univ La Paz, Spine Surg Unit, Madrid, Spain
[13] Harvard Med Sch, Brigham & Womens Hosp, Providence, RI 02912 USA
[14] Brown Univ, Warren Alpert Sch Med, Dept Orthopaed Surg, Providence, RI USA
[15] Univ Calif San Francisco, Davis, CA USA
[16] Univ Calif Davis, Dept Orthoped Surg, Sacramento, CA USA
[17] Washington Univ St Louis, Dept Orthopaed Surg, St Louis, MO USA
[18] Johns Hopkins Med Inst, Dept Orthopaed Surg, Baltimore, MD USA
[19] Rady Childrens Hosp, Dept Orthopaed Surg, San Diego, CA USA
[20] Swedish Neurosci Inst, Dept Orthopaed Surg, Seattle, WA USA
[21] Schulthess Klin, Spine Ctr Div, Dept Orthoped & Neurosurg, Zurich, Switzerland
[22] Bordeaux Univ Hosp, Spine Surg Unit, Bordeaux, France
[23] Duke Univ, Sch Med, Dept Neurosurg, Spine Div, Durham, NC USA
[24] Duke Univ, Sch Med, Dept Orthopaed Surg, Spine Div, Durham, NC USA
[25] Rocky Mt Scoliosis & Spine, Denver, CO USA
关键词
adult spinal deformity; spine; cost-utility; risk stratification; major complications; mechanical failure; surgical factors; OSWESTRY DISABILITY INDEX; NUMERIC RATING-SCALES; FRAILTY INDEX; OUTCOMES; VALIDATION; IMPACT; PREDICTORS; PARAMETERS; BACK;
D O I
10.1177/21925682231212966
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study design/setting: Retrospective cohort study. Objective: Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery. Methods: ASD patients with 2-year (2Y) data were included. Tertiles were used to define high degrees of frailty, sagittal deformity, blood loss, and surgical time. Cost was calculated using the Pearl Diver registry and cost-utility at 2Y was compared between cohorts based on the number of risk factors present. Statistically significant differences in cost-utility by number of baseline risk factors were determined using ANOVA, followed by a generalized linear model, adjusting for clinical site and surgeon, to assess the effects of increasing risk score on overall cost-utility. Results: By 2 years, 31% experienced a major complication and 23% underwent reoperation. Patients with <= 2 risk factors had significantly less major complications. Patients with 2 risk factors improved the most from baseline to 2Y in ODI. Average cost increased by $8234 per risk factor (R-2 = .981). Cost-per-QALY at 2Y increased by $122,650 per risk factor (R-2 = .794). Adjusted generalized linear model demonstrated a significant trend between increasing risk score and increasing cost-utility (r(2) = .408, P < .001). Conclusions: The number of defined patient-specific and surgical risk factors, especially those with greater than two, were associated with increased index surgical costs and diminished cost-utility. Efforts to optimize patient physiology and minimize surgical risk would likely reduce healthcare expenditures and improve the overall cost-utility profile for ASD interventions.Level of evidence: III.
引用
收藏
页码:818 / 830
页数:13
相关论文
共 43 条
  • [1] Impact of Frailty on Outcomes Following Spine Surgery: A Prospective Cohort Analysis of 668 Patients
    Agarwal, Nitin
    Goldschmidt, Ezequiel
    Taylor, Tavis
    Roy, Souvik
    Dunn, Stefanie C. Altieri
    Bilderback, Andrew
    Friedlander, Robert M.
    Kanter, Adam S.
    Okonkwo, David O.
    Gerszten, Peter C.
    Hamilton, D. Kojo
    Hall, Daniel E.
    [J]. NEUROSURGERY, 2021, 88 (03) : 552 - 557
  • [2] 5-Year Reoperation Risk and Causes for Revision After Idiopathic Scoliosis Surgery
    Ahmed, Syed Imraan
    Bastrom, Tracey P.
    Yaszay, Burt
    Newton, Peter O.
    [J]. SPINE, 2017, 42 (13) : 999 - 1005
  • [3] Reliability assessment of a novel cervical spine deformity classification system
    Ames, Christopher P.
    Smith, Justin S.
    Eastlack, Robert
    Blaskiewicz, Donald J.
    Shaffrey, Christopher I.
    Schwab, Frank
    Bess, Shay
    Kim, Han Jo
    Mundis, Gregory M., Jr.
    Klineberg, Eric
    Gupta, Munish
    O'Brien, Michael
    Hostin, Richard
    Scheer, Justin K.
    Protopsaltis, Themistocles S.
    Fu, Kai-Ming G.
    Hart, Robert
    Albert, Todd J.
    Riew, K. Daniel
    Fehlings, Michael G.
    Deviren, Vedat
    Lafage, Virginie
    [J]. JOURNAL OF NEUROSURGERY-SPINE, 2015, 23 (06) : 673 - 683
  • [4] Impact of Magnitude and Percentage of Global Sagittal Plane Correction on Health-Related Quality of Life at 2-Years Follow-Up
    Blondel, Benjamin
    Schwab, Frank
    Ungar, Benjamin
    Smith, Justin
    Bridwell, Keith
    Glassman, Steven
    Shaffrey, Christopher
    Farcy, Jean-Pierre
    Lafage, Virginie
    [J]. NEUROSURGERY, 2012, 71 (02) : 341 - 348
  • [5] Complication Risk in Primary and Revision Minimally Invasive Lumbar Interbody Fusion: A Comparable Alternative to Conventional Open Techniques?
    Bortz, Cole
    Alas, Haddy
    Segreto, Frank
    Horn, Samantha R.
    Varlotta, Christopher
    Brown, Avery E.
    Pierce, Katherine E.
    Ge, David H.
    Vasquez-Montes, Dennis
    Lafage, Virginie
    Lafage, Renaud
    Fischer, Charla R.
    Gerling, Michael C.
    Protopsaltis, Themistocles S.
    Buckland, Aaron J.
    Sciubba, Daniel M.
    De La Garza-Ramos, Rafael
    Passias, Peter G.
    [J]. GLOBAL SPINE JOURNAL, 2020, 10 (05) : 619 - 626
  • [6] The pros and cons to saving the L5-S1 motion segment in a long scoliosis fusion construct
    Bridwell, KH
    Edwards, CC
    Lenke, LG
    [J]. SPINE, 2003, 28 (20) : S234 - S242
  • [7] A cost utility analysis of treating different adult spinal deformity frailty states
    Brown, Avery E.
    Lebovic, Jordan
    Alas, Haddy
    Pierce, Katherine E.
    Bortz, Cole A.
    Ahmad, Waleed
    Naessig, Sara
    Hassanzadeh, Hamid
    Labaran, Lawal A.
    Puvanesarajah, Varun
    Vasquez-Montes, Dennis
    Wang, Erik
    Raman, Tina
    Diebo, Bassel G.
    Vira, Shaleen
    Protopsaltis, Themistocles S.
    Lafage, Virginie
    Lafage, Renaud
    Buckland, Aaron J.
    Gerling, Michael C.
    Passias, Peter G.
    [J]. JOURNAL OF CLINICAL NEUROSCIENCE, 2020, 80 : 223 - 228
  • [8] Estimating EQ-5D Values From the Oswestry Disability Index and Numeric Rating Scales for Back and Leg Pain
    Carreon, Leah Y.
    Bratcher, Kelly R.
    Das, Nandita
    Nienhuis, Jacob B.
    Glassman, Steven D.
    [J]. SPINE, 2014, 39 (08) : 678 - 682
  • [9] Predicting SF-6D Utility Scores From the Oswestry Disability Index and Numeric Rating Scales for Back and Leg Pain
    Carreon, Leah Y.
    Glassman, Steven D.
    McDonough, Christine M.
    Rampersaud, Raja
    Berven, Sigurd
    Shainline, Michael
    [J]. SPINE, 2009, 34 (19) : 2085 - 2089
  • [10] Validation of new clinical quantitative analysis software applicable in spine orthopaedic studies
    Champain, S.
    Benchikh, K.
    Nogier, A.
    Mazel, C.
    Guise, J. De.
    Skalli, W.
    [J]. EUROPEAN SPINE JOURNAL, 2006, 15 (06) : 982 - 991