Age-Related Macular Degeneration in an Ageing Society - Current Epidemiological Research

被引:11
作者
Brandl, Caroline [1 ,2 ]
Finger, Robert Patrick [3 ,4 ]
Heid, Iris Maria [2 ]
Mauschitz, Matthias Marten [4 ]
机构
[1] Univ Regensburg, UnivAugenklin Regensburg, Fak Med, Franz Josef Str Allee 11, D-93053 Regensburg, Germany
[2] Univ Regensburg, Lehrstuhl Genet Epidemiol, Fak Med, Regensburg, Germany
[3] Heidelberg Univ, Univ Med Mannheim, Univ Augenklin, Med Fak Mannheim, Mannheim, Germany
[4] Univ Bonn, Univ Augenklin Bonn, Bonn, Germany
关键词
age-related macular degeneration (AMD); prevalence; incidence; risk factors; population-based studies; demographic development; RISK-FACTORS; SEVERITY SCALE; EYE DISEASE; PREVALENCE; PROGRESSION; MACULOPATHY; AREDS; CLASSIFICATION;
D O I
10.1055/a-2105-1064
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Epidemiological studies on age-related macular degeneration (AMD) provide crucial data on the frequency of early and late forms as well as associated risk factors. The increasing number of population- based cross-sectional and longitudinal cohort studies in Germany and Europe with published data is making prevalence and incidence estimators for AMD more robust, although they show mostly method-related fluctuations. This review article brings together the latest published epidemiological measures for AMD from Germany and Central as well as Western Europe. Based on this data and population figures for Germany and Europe, prevalence is projected, and future trends are forecasted. The epidemiological evidence for AMD-associated risk factors is also improving, especially through meta-analyses within large consortia with correspondingly high case numbers. This review article summarizes the latest findings and resulting recommendations for prevention approaches. Additionally, it discusses treatment options and future challenges.
引用
收藏
页码:1052 / 1059
页数:8
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