Immunoglobulin A vasculitis (formerly Schoenlein-Henoch purpura)-An update

被引:0
作者
Hospach, Toni [1 ,4 ]
Mueller, Dominik [2 ]
Pohl, Martin [3 ]
机构
[1] Olgahospital, Zent Padiat Rheumatol Klinikum Stuttgart ZEPRAS, Padiat 2, Stuttgart, Germany
[2] Charite Univ Med Berlin, Klin Padiat m?S Gastroenterol Nephrol & Stoffwechs, Berlin, Germany
[3] Univ Klinikum Freiburg, Zent Kinder & Jugendmed, Sekt Kindernephrol, Freiburg, Germany
[4] Olgahospital, Zent Padiat Rheumatol Klinikum Stuttgart ZEPRAS, Padiat 2, Kriegsbergstr 62, D-70176 Stuttgart, Germany
关键词
Hematuria; Proteinuria; Steroids; Nephritis; Skin manifestations; SCHONLEIN PURPURA; IGA NEPHROPATHY; CHILDHOOD; CLASSIFICATION; EXPERIENCE; NEPHRITIS; DISEASE; RISK;
D O I
10.1007/s00112-023-01770-2
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Immunoglobulin (Ig) A vasculitis (IgAV, formerly Schoenlein-Henoch purpura) is a systemic immune complex-mediated vasculitis of small vessels clinically characterized by the triad of palpable purpura, abdominal and joint pain. It is the most frequent vasculitis of childhood and adolescence. The diagnosis is based on clinical findings. The cutaneous vasculitis predominantly shows spontaneous remission. Renal involvement is common and with variable severity. Acute renal failure, nephrotic syndrome and long-term renal sequelae can develop in severe cases.
引用
收藏
页码:645 / 655
页数:11
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