Demixing of homogeneous binary lipid membranes induced by protein inclusions

被引:1
作者
Nowakowski, Piotr [1 ,2 ,3 ]
Stumpf, Bernd Henning [3 ]
Smith, Ana-Suncana [3 ,4 ]
Maciolek, Anna [1 ,3 ,5 ]
机构
[1] Max Planck Inst Intelligente Syst Stuttgart, Heisenbergstr 3, D-70569 Stuttgart, Germany
[2] Univ Stuttgart, Inst Theoret Phys 4, Pfaffenwaldring 57, D-70569 Stuttgart, Germany
[3] Rudjer Boskovic Inst, Div Phys Chem, Grp Computat Life Sci, Bijenicka 54, Zagreb 10000, Croatia
[4] Friedrich Alexander Univ Erlangen Nurnberg, Inst Theoret Phys, PULS Grp, IZNF, Cauerstr 3, D-91058 Erlangen, Germany
[5] Polish Acad Sci, Inst Phys Chem, Kasprzaka 44-52, PL-01224 Warsaw, Poland
关键词
ORGANIZATION; BILAYERS; FLUCTUATIONS; TRANSITIONS; SIMULATION; ADHESION; MODEL; DECAY;
D O I
10.1103/PhysRevE.107.054120
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We study a model of a lipid bilayer membrane described by two order parameters: the chemical composition described using the Gaussian model and the spatial configuration described with the elastic deformation model of a membrane with a finite thickness or, equivalently, for an adherent membrane. We assume and explain on physical grounds the linear coupling between the two order parameters. Using the exact solution, we calculate the correlation functions and order parameter profiles. We also study the domains that form around inclusions on the membrane. We propose and compare six distinct ways to quantify the size of such domains. Despite its simplicity, the model has many interesting features like the Fisher-Widom line and two distinct critical regions.
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页数:26
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