Force-Triggered Guest Release from Mechanophore Incorporated Rotaxanes

被引：13
作者：
Yang, Jinghui [1 ]
Xia, Yan [1 ]
机构：
[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
来源：
CCS CHEMISTRY | 2023年 / 5卷 / 06期
关键词：
mechanochemistry; rotaxane; mechanophore; polymer; release of molecules; MECHANOCHEMISTRY; POLYMERIZATION;
D O I：
10.31635/ccschem.023.202302749
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed a rotaxane-based mechanophore system that is capable of breaking a mechanical bond and releasing small molecules via force-triggered rotaxane disassembly. In this design, a cyclobutane mechanophore was fused to the ring component of a rotaxane, constructed through a template-mediated synthesis in high yields. Upon opening the ring component, the rotaxane disassembled to release the axle molecule. We successfully demonstrated and quantified the force-triggered release of the axle molecule in both solution and solid-state samples. [GRAPHICS] .
引用
收藏
页码：1365 / 1371
页数：7
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