Curcumin nanoparticles and the therapeutic potential of curcumin for musculoskeletal disorders

被引：1

作者：

Wu, H. -y. ^{[1
,2
]}

Yu, H. -t. ^{[3
]}

Kang, B. ^{[1
,2
]}

Xuan, Y. -y. ^{[4
]}

Zhang, H. -q. ^{[1
]}

Li, X. -s. ^{[1
]}

机构：

[1] 940 th Hosp Joint Logist Support Force Chinese Peo, Dept Joint Surg, Lanzhou, Gansu, Peoples R China

[2] Ningxia Med Univ, Sch Clin Med, Yinchuan, Peoples R China

[3] Gansu Univ Chinese Med, Lanzhou, Peoples R China

[4] 940th Hosp Joint Logist Support Force Chinese Peop, Fundamental Med Sci Res Labs, Lanzhou, Gansu, Peoples R China

来源：

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2023年 / 27卷 / 20期

关键词：

Musculoskeletal; Curcumin; Nanomaterials; Osteo-porosis; Osteoarthritis; GLUCOCORTICOID-INDUCED OSTEOPOROSIS; IN-VITRO; GOLD NANOPARTICLES; CLINICAL-TRIAL; DOUBLE-BLIND; TETRAHYDROCURCUMIN; ARTHRITIS; BIOAVAILABILITY; INFLAMMATION; LIPOSOMES;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

- Musculoskeletal disorders (MSD) are a collection of degenerative conditions im-pacting the body's bones, joints, muscles, ten-dons, ligaments, and nerves. MSDs affect ap-proximately 1.71 billion individuals worldwide and are a significant cause of disability. Cur -cumin is a polyphenolic compound with anti-in-flammatory, antioxidant, and antitumor proper-ties. In this review, we will discuss the research progress of structural analogs, derivatives, and nanomaterials that can improve the bioavailabil-ity of this natural drug. Curcumin may potential-ly retard the progression of osteoporosis, osteo-arthritis, and rheumatoid arthritis. These effects may be related to curcumin's targeting of multi-ple signalling pathways.

引用

页码：9680 / 9702

页数：23

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