Prevalence of risk and factors associated with obstructive sleep apnea-hypopnea syndrome in an adult population in Kinshasa, Democratic Republic of Congo

被引:5
作者
Tete, Boniface [1 ,2 ]
Albdewi, Mohamad Ammar [2 ]
Nkodila, Aliocha [3 ]
Muhala, Blaise [4 ]
Akilimali, Pierre [5 ]
Bisuta, Serge [1 ]
Makulo, Jean Robert [6 ]
Kayembe, Jean Marie [1 ]
机构
[1] Univ Kinshasa, Fac Med, Univ Clin Kinshasa, Sleep Explorat Unit,Dept Internal Med,Dept Pulmo, Kinshasa 123 XI, DEM REP CONGO
[2] Ctr Hosp Arpajon, Dept Pulmonol, Sleep Explorat Unit, Arpajon, France
[3] Protestant Univ Congo, Dept Family Med & Primary Hlth Care, Fac Med, Kinshasa, DEM REP CONGO
[4] Univ Kinshasa, Dept Math & Comp Sci, Fac Sci, Kinshasa, DEM REP CONGO
[5] Univ Kinshasa, Sch Publ Hlth, Fac Med, Kinshasa, DEM REP CONGO
[6] Univ Kinshasa, Univ Clin Kinshasa, Dept Nephrol, Dept Internal Med,Fac Med, Kinshasa, DEM REP CONGO
关键词
Kinshasa; obstructive sleep apnea-hypopnea syndrome; prevalence; risk factors; STOP-BANG; INTERMITTENT HYPOXIA; GENERAL-POPULATION;
D O I
10.1111/jsr.13637
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is an underdiagnosed and lesser known disease in sub-Saharan Africa. We believe that this is the first descriptive and analytical cross-sectional study in Kinshasa (from February 1 to October 31, 2021), which included respondents aged >= 18 years. The study aimed to determine the prevalence of the risk and factors associated with OSAHS. Each participant signed a free and informed consent. Statistical analyses were performed using XLStat 2020 and the Statistical Package for the Social Sciences version 24 for Windows. Odds ratios (ORs) were calculated to determine the degree of association between these variables and a high risk of OSAHS. The significance threshold was p < 0.05 and confidence interval (CI) at 95%. There were 4,162 participants, including 2,287 men (54.9%), with an mean (SD) age of 32 +/- 12.6 years. The prevalence of OSAS risk was 17.4% and 7.9% for men and women, respectively. The associated risk factors were male sex (OR 4, 95% CI 3.20-5.54), hypertension (OR 6.7, 95% CI 4.87-9.30), age >= 60 years (OR 8.7, 95% CI 4.07-18.88), obesity/overweight (OR 1.94, 95% CI 1.13-3.78), and excessive daytime sleepiness (OR 2.63, 95% CI 2.05-3.56). The risk of OSAS in Kinshasa is high and it increases with age, male sex, obesity, and hypertension. The Snoring, Tiredness, Observed apnea, high blood Pressure, Body mass index, Age, Neck circumference, and male Gender (STOP-BANG) questionnaire is an easy-to-use tool for diagnostic orientation.
引用
收藏
页数:10
相关论文
共 27 条
[1]  
Akanbi Maxwell O, 2017, J Med Trop, V19, P110, DOI 10.4103/jomt.jomt_17_17
[2]   Insomnia symptoms combined with nocturnal hypoxia associate with cardiovascular comorbidity in the European sleep apnea cohort (ESADA) [J].
Anttalainen, Ulla ;
Grote, L. ;
Fietze, I. ;
Riha, R. L. ;
Ryan, S. ;
Staats, R. ;
Hedner, J. ;
Saaresranta, T. ;
Anttalainen, U. ;
Barbe, F. ;
Bonsignore, M. R. ;
Basoglu, O. ;
Bielicki, P. ;
Bouloukaki, I. ;
Dogas, Z. ;
Dorkova, Z. ;
Escourrou, P. ;
Fietze, I ;
Esquinas, C. ;
Grote, L. ;
Hayes, L. ;
Hedner, J. ;
Joppa, P. ;
Kurki, S. ;
Kvamme, J. A. ;
Tamisier, R. ;
Lombardi, C. ;
Marrone, O. ;
Masa, J. F. ;
McNicholas, W. T. ;
Montserrat, J. M. ;
Parati, G. ;
Pataka, A. ;
Penzel, T. ;
Pepin, J. L. ;
Pretl, M. ;
Riha, R. L. ;
Roisman, G. ;
Ryan, S. ;
Saaresranta, T. ;
Schiza, S. E. ;
Schulz, R. ;
Sliwinski, P. ;
Staats, R. ;
Steiropoulos, P. ;
Tasbakan, M. S. ;
Tkacova, R. ;
Varoneckas, G. ;
Verbraecken, J. ;
Vrints, H. .
SLEEP AND BREATHING, 2019, 23 (03) :805-814
[3]   Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis [J].
Benjafield, Adam V. ;
Ayas, Najib T. ;
Eastwood, Peter R. ;
Heinzer, Raphael ;
Ip, Mary S. M. ;
Morrell, Mary J. ;
Nunez, Carlos M. ;
Patel, Sanjay R. ;
Penzel, Thomas ;
Pepin, Jean-Louis D. ;
Peppard, Paul E. ;
Sinha, Sanjeev ;
Tufik, Sergio ;
Valentine, Kate ;
Malhotra, Atul .
LANCET RESPIRATORY MEDICINE, 2019, 7 (08) :687-698
[4]   Effects of age on sleep apnea in men I. Prevalence and severity [J].
Bixler, EO ;
Vgontzas, AN ;
Ten Have, T ;
Tyson, K ;
Kales, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 157 (01) :144-148
[5]   Surgical vs Conventional Therapy for Weight Loss Treatment of Obstructive Sleep Apnea A Randomized Controlled Trial [J].
Dixon, John B. ;
Schachter, Linda M. ;
O'Brien, Paul E. ;
Jones, Kay ;
Grima, Mariee ;
Lambert, Gavin ;
Brown, Wendy ;
Bailey, Michael ;
Naughton, Matthew T. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 308 (11) :1142-1149
[6]   Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr [J].
Durán, J ;
Esnaola, S ;
Rubio, R ;
Iztueta, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :685-689
[7]   Physiological and genomic consequences of intermittent hypoxia -: Invited Review:: Physiological consequences of intermittent hypoxia:: systemic blood pressure [J].
Fletcher, EC .
JOURNAL OF APPLIED PHYSIOLOGY, 2001, 90 (04) :1600-1605
[8]   Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study [J].
Heinzer, R. ;
Vat, S. ;
Marques-Vidal, P. ;
Marti-Soler, H. ;
Andries, D. ;
Tobback, N. ;
Mooser, V. ;
Preisig, M. ;
Malhotra, A. ;
Waeber, G. ;
Vollenweider, P. ;
Tafti, M. ;
Haba-Rubio, J. .
LANCET RESPIRATORY MEDICINE, 2015, 3 (04) :310-318
[9]   Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea [J].
Jelic, Sanja ;
Padeletti, Margherita ;
Kawut, Steven M. ;
Higgins, Christopher ;
Canfield, Stephen M. ;
Onat, Duygu ;
Colombo, Paolo C. ;
Basner, Robert C. ;
Factor, Phillip ;
LeJemtel, Thierry H. .
CIRCULATION, 2008, 117 (17) :2270-2278
[10]   A sleep apnea prediction model developed for African Americans: the Jackson Heart Sleep Study [J].
Johnson, Dayna A. ;
Sofer, Tamar ;
Guo, Na ;
Wilson, James ;
Redline, Susan .
JOURNAL OF CLINICAL SLEEP MEDICINE, 2020, 16 (07) :1171-1178