Multilayer microparticles for programmed sequential release of phenolic compounds from Eugenia stipitata: Stability and bioavailability

被引:3
作者
de Oliveira, Williara Queiroz [1 ,8 ]
Numa, Iramaia Angelica Neri [1 ]
Alvim, Izabela D. [2 ]
Azeredo, Henriette M. C. [3 ]
Santos, Leticia B. [3 ,4 ]
Borsoi, Felipe T. [1 ]
de Araujo, Fabio F. [1 ,5 ]
Sawaya, Alexandra C. H. F. [5 ]
do Nascimento, Gustavo C. [6 ]
Clerici, Maria Teresa P. S. [6 ]
do Sacramento, Celio K. [7 ]
Pastore, Glaucia Maria [1 ]
机构
[1] Univ Estadual Campinas, Fac Food Engn, Dept Food Sci, Lab Bioflavours & Bioact Cpds, BR-13083862 Campinas, SP, Brazil
[2] Food Technol Inst ITAL, Technol Ctr Cereal & Chocolate, BR-13070178 Campinas, SP, Brazil
[3] Embrapa Instrumentat, R 15 Novembro 1452, BR-13560970 Sao Carlos, SP, Brazil
[4] UNESP Sao Paulo State Univ, Grad Program Food Nutr & Food Engn, Rodovia Araraquara Jau,km 01, BR-14800903 Araraquara, SP, Brazil
[5] Univ Estadual Campinas, Fac Pharmaceut Sci, BR-13083871 Campinas, SP, Brazil
[6] Univ Estadual Campinas, Sch Food Engn, Dept Food Sci & Nutr, BR-13083862 Campinas, SP, Brazil
[7] Univ Estadual Santa Cruz, Dept Agr & Environm Sci, BR-45662900 Ilheus, BA, Brazil
[8] Univ Estadual Campinas, Fac Food Engn, Dept Food Sci, Lab Bioflavours & Bioact Cpds, Monteiro Lobato St, 80, BR-13083862 Campinas, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
Araca-boi; Cara-roxo; Co; -encapsulation; In vitro digestion; Spray drying; Spray chilling; MICROENCAPSULATION; NANOPARTICLES; EXTRACT; FOOD; GUM;
D O I
10.1016/j.foodchem.2024.138579
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A co-delivery system based on multilayer microparticles was developed and characterized for the sequential release of phenolic compounds (PCs) using different encapsulation processes (spray drying: SD and drying-chilling spray: SDC) and wall materials to improve the stability and bioavailability of PCs. Samples were characterized in terms of process yield (PY%), phenolic retention efficiency (PRE%), chemical structure and crystallinity (NMR, FTIR, DXR), thermal stability (DSC and FT-IR), anti-radical capacity (ORAC and ABTS) and in vitro digestion. PRE% of samples by SD were higher (p < 0.05) than SDC due to the formation of PCs from CRF (car & aacute;-roxo flour). NMR, FTIR, DXR confirmed the presence of key components and interactions for the formation of the advanced co-delivery system. The SDC particles showed crystalline regions by XRD and were stable at similar to 47 degrees C. All samples showed good release of PC in the intestinal phase, and antiradical capacity that reached 23.66 mu mol TE g(-1).
引用
收藏
页数:12
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共 39 条
[31]   Formulation and Stability Assessment of Bakery Snacks Enriched with Encapsulated Phenolic Compounds from Lemnian Tomatoes and Pumpkin (Cucurbita moschata) [J].
Michalaki, Afroditi ;
Karantonis, Haralabos C. .
APPLIED SCIENCES-BASEL, 2024, 14 (13)
[32]   Storage and Baking Stability of Encapsulated Sour Cherry Phenolic Compounds Prepared from Micro- and Nano-Suspensions [J].
Luca, Alexandru ;
Cilek, Betul ;
Hasirci, Vasif ;
Sahin, Serpil ;
Sumnu, Gulum .
FOOD AND BIOPROCESS TECHNOLOGY, 2014, 7 (01) :204-211
[33]   An efficient co-delivery system based on multilayer structural nanoparticles for programmed sequential release of resveratrol and vitamin D3 to combat dextran sodium sulfate-induced colitis in mice [J].
Wang, Luhui ;
Wei, Zihao ;
Lv, Ling ;
Xue, Changhu .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 254
[34]   Loading and release of phenolic compounds from mexican oregano ( Lippia graveolens) ) in different Cationic-PEGylated matrixes and their effect on CACO-2 and CCD-18co cells [J].
Garcia-Carrasco, Melissa ;
Picos-Corrales, Lorenzo A. ;
Contreras-Angulo, Laura ;
Gutierrez-Grijalva, Erick P. ;
Angulo-Escalante, Miguel Angel ;
Licea-Claverie, Angel ;
Heredia, Basilio .
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2024, 100
[35]   Stability and programmed sequential release of Lactobacillus plantarum and curcumin encapsulated in bilayer-stabilized W1/O/W2 double emulsion: Effect of pectin as protective shell [J].
Hua, Yijie ;
Wei, Zihao ;
Xue, Changhu ;
Si, Jingyu .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 265
[36]   Application of the INFOGEST Standardized Method to Assess the Digestive Stability and Bioaccessibility of Phenolic Compounds from Galician Extra-Virgin Olive Oil [J].
Reboredo-Rodriguez, P. ;
Olmo-Garcia, L. ;
Figueiredo-Gonzalez, M. ;
Gonzalez-Barreiro, C. ;
Carrasco-Pancorbo, A. ;
Cancho-Grande, B. .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 69 (39) :11592-11605
[37]   Effect of solid-state fermentation over the release of phenolic compounds from brewer's spent grain revealed by UPLC-MSE [J].
Maia, Ingrid da Costa ;
dos Santos D'Almeida, Carolina Thomaz ;
Guimaraes Freire, Denise Maria ;
Costa Cavalcanti, Elisa d'Avila ;
Cameron, Luiz Claudio ;
Dias, Juliana Furtado ;
Larraz Ferreira, Mariana Simoes .
LWT-FOOD SCIENCE AND TECHNOLOGY, 2020, 133
[38]   Oil-Based Double Emulsion Microcarriers for Enhanced Stability and Bioaccessibility of Betalains and Phenolic Compounds from Opuntia stricta var. dillenii Green Extracts [J].
Parralejo-Sanz, Sara ;
Gomez-Lopez, Ivan ;
Gonzalez-Alvarez, Erika ;
Montiel-Sanchez, Mara ;
Cano, M. Pilar .
FOODS, 2023, 12 (11)
[39]   Influence of extrusion process on the release of phenolic compounds from mango (Mangifera indica L.) bagasse-added confections and evaluation of their bioaccessibility, intestinal permeability, and antioxidant capacity [J].
Abril Herrera-Cazares, Luz ;
Luzardo-Ocampo, Ivan ;
Ramirez-Jimenez, Aurea K. ;
Gutierrez-Uribe, Janet A. ;
Campos-Vega, Rocio ;
Gaytan-Martinez, Marcela .
FOOD RESEARCH INTERNATIONAL, 2021, 148 (148)