Palladium-Catalyzed Asymmetric Hydrofunctionalizations of Conjugated Dienes

Because of the broad substrate availability, high atom economy and efficient stereocontrol, palladium-catalzyed asymmetric hydrofunctionalizations of conjugated dienes have emerged as an efficient route to construct enantioenriched allylic motifs, including allylic C-C, C-N, C-S, C-P, C-Si and C-O bonds. The development, advance and mechanistic features of this area in the past decades are summarized. Based on the types of allylic stereogenic centers constructed via this strategy, the review is divided into six parts, including asymmetric hydroalkylation, hydroamination, hydrophosphinylation, hydrosulfonylation, hydrosilylation and hydroalkoxylation.