Growth of non-enzymatic cholesterol biosensor using TiO2 decorated graphene oxide with bare GCE and PPy-GCE

被引:6
作者
Deivanayaki, S. [1 ]
Jayamurugan, P. [2 ]
Ashokan, S. [3 ]
Krishnan, V. Gopala [4 ]
Yogeswari, B. [5 ]
Ubaidullah, Mohd [6 ]
Pandit, Bidhan [7 ]
Sarma, G. V. S. S. [8 ]
Narsetti, Hemanth Kumar [9 ]
机构
[1] Sri Ramakrishna Engn Coll, Dept Phys, Coimbatore 641022, Tamilnadu, India
[2] Sri Ramakrishna Mission Vidyalaya Coll Arts & Sci, Dept Phys, Coimbatore 641020, Tamilnadu, India
[3] Bannari Amman Inst Technol, Dept Phys, Erode 638401, Tamilnadu, India
[4] DR NGP Arts & Sci Coll, Dept Phys, Coimbatore 641048, Tamilnadu, India
[5] Sri Eshwar Coll Engn, Dept Phys, Coimbatore 641202, India
[6] King Saudi Univ, Dept Chem Coll Sci, Riyadh 11451, Saudi Arabia
[7] Universidad, Dept Mat Sci & Engn & Chem Engn, Carlosde Madrid 3, Ave Univ 30, Leganes 28911, Madrid, Spain
[8] Malla Reddy Engn Coll A Maisammaguda, Dept Phys, Malkajgiri Secundrabad 500100, Telangana, India
[9] St Peters Engn Coll, Dept Phys, Hyderabad 500100, India
关键词
Clinical analysis; Non-enzymatic; Nanomaterials; Chemical oxidative polymerization; PHOTOCATALYTIC DEGRADATION; ELECTROCHEMICAL SENSOR; VANILLIN; COMPOSITE; NANOCOMPOSITES; NANOMATERIALS; SENSITIVITY; FABRICATION;
D O I
10.1016/j.jics.2023.100906
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this work, we report an electrochemical cholesterol biosensor based on cholesterol oxidase(ChOx) enzyme immobilized on TiO2- nanoparticles - reduced graphene oxide(rGO) - polypyrrole (PPy) nanocomposite modified electrode.The electrochemical properties of GCE modified PPy (PPy-GCE) were studied using CV (Cyclic Vol-tammetry) and DPV (Differential Pulse Voltammetry). The developed sensor exhibited piecewise linearity from 0.1 mu M to 1 mu M and from 1 mu M to 600 mu M with the sensitivity of 61.665 and 0.1466 (2 mA mM x cm) respectively. The limit of detection of the sensor was found to be 32 nm.
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页数:7
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