Synthesis of New Imidazolidin-2-ones Based on the Reaction of 1-(2,2-Dimethoxyethyl)urea with C-Nucleophiles

被引：0
|
作者：
Smolobochkin, A. V. [1 ]
Kuznetsova, E. A. [1 ]
Gazizov, A. S. [1 ]
Burilov, A. R. [1 ]
Pudovik, M. A. [1 ]
机构：
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, Fed Res Ctr, Kazan Sci Ctr, Kazan 420088, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 06期
关键词：
acetals; imidazolidin-2-one; 1-(2; 2-dimethoxyethyl)urea; C-nucleophiles; UREA; HETEROCYCLES; INHIBITION; DIVERSITY;
D O I：
10.1134/S1070363223060026
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The acid-catalyzed reaction of 1-(2,2-dimethoxyethyl)ureas with aromatic and heterocyclic nucleophiles leads to the formation of new imidazolidin-2-ones. The proposed method makes it quite easy to introduce the desired pharmacophore group into position 4 of the imidazolidine ring.
引用
收藏
页码：1322 / 1326
页数：5
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