Longitudinal Transcriptomic Analysis of CAR-T Cells at Single-Cell Level Allows the Identification of Molecular Mechanisms Promoting Long-Term CAR-T Cell Persistence in MM

被引：0

作者：

Rodriguez-Madoz, Juan Roberto ^{[1
,2
]}

Jordana-Urriza, Lorea ^{[1
]}

Serrano, Guillermo ^{[3
]}

Oliver-Caldes, Aina ^{[4
]}

Calleja-Cervantes, Maria Erendira ^{[1
,3
]}

San-Martin, Patxi ^{[1
]}

Vilas-Zornoza, Amaia ^{[1
,2
]}

Ullate-Agote, Asier ^{[1
,2
]}

Zabaleta, Aintzane ^{[1
,2
,5
]}

Alignani, Diego ^{[1
,5
]}

Lozano, Teresa ^{[6
]}

Cabanas Perianes, Valentin ^{[7
]}

Luis Reguera, Juan ^{[8
]}

Navarro-Bailon, Almudena ^{[9
]}

Espanol-Rego, Marta ^{[10
]}

Pascal, Mariona ^{[10
]}

Maria Moraleda, Jose ^{[7
]}

Perez-Simon, Jose A. ^{[8
]}

Victoria Mateos, Maria ^{[2
,9
]}

Sanchez-Guijo Martin, Fermin ^{[2
,11
]}

Urbano-Ispizua, Alvaro ^{[4
]}

Juan, Manel ^{[10
]}

Alfonso Pierola, Ana ^{[2
,12
,13
]}

Rifon, Jose J. ^{[2
,12
,13
]}

Rodriguez Otero, Paula ^{[2
,3
,12
,13
]}

Paiva, Bruno ^{[1
,2
,14
]}

Inoges, Susana ^{[2
,13
]}

Lopez-Diaz De Cerio, Ascension ^{[2
,13
,15
]}

Lasarte, Juan J. ^{[12
]}

San Miguel, Jesus ^{[2
,12
,16
]}

Fernandez de larrea, Carlos ^{[4
]}

Hernaez, Mikel ^{[2
,3
,17
]}

Prosper, Felipe ^{[1
,2
,12
,13
]}

机构：

[1] Cima Univ Navarra, Hematooncol Program, IdiSNA, Pamplona, Spain

[2] Ctr Invest Biomed Red Canc CIBERONC, Madrid, Spain

[3] Cima Univ Navarra, Computat Biol Program, IdiSNA, Pamplona, Spain

[4] Univ Barcelona, Dept Hematol, IDIBAPS, Hosp Clin Barcelona, Barcelona, Spain

[5] Cima Univ Navarra, Flow Cytometry Core, IdiSNA, Pamplona, Spain

[6] Cima Univ Navarra, Immunol & Immunotherapy Program, IdiSNA, Pamplona, Spain

[7] Univ Murcia, Dept Hematol, IMIB, Virgen Arrixaca Univ Hosp, Murcia, Spain

[8] Univ Seville, Dept Hematol, Univ Hosp Virgen Rocio, IBIS, Seville, Spain

[9] Univ Salamanca, Hematol Dept, IBSAL, Univ Hosp Salamanca, Salamanca, Spain

[10] Univ Barcelona, Dept Immunol, Hosp Clin Barcelona, IDIBAPS, Barcelona, Spain

[11] USAL, Hosp Univ Salamanca, Inst Invest Biomed Salamanca IBSAL, Ctr Invest Canc,IBMCC,CSIC, Salamanca, Spain

[12] Canc Ctr Univ Navarra CCUN, Pamplona, Spain

[13] Clin Univ Navarra, IdiSNA, Hematol & Cell Therapy Dept, Pamplona, Spain

[14] Canc Ctr Clin Univ Navarra CCUN, Flow Cytometry Core, Ctr Appl Med Res CIMA, Inst Invest Sanitarias Navarra IdiSNA, Pamplona, Spain

[15] Clin Univ Navarra, Immunol & Immunotherapy Dept, Pamplona, Spain

[16] Canc Ctr Clin Univ Navarra CCUN, CIMA, CIBERONC, IDISNA, Pamplona, Spain

[17] Univ Navarra, Data Sci & Artificial Intelligence Inst DATAI, Pamplona, Spain

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-182933

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：5