Advances in the Study of Selenium-Enriched Probiotics: From the Inorganic Se into Se Nanoparticles

Selenium (Se) is a momentous metallic element that plays an irreplaceable role in biochemical activities. Se deficiency remains a nutritional challenge across the world. Organic Se supplementation is the most effective treatment means for Se deficiency. Organic Se transformed from Se-enriched probiotics show outstanding excellent properties in antibacteria, anti-oxidation, anti-inflammation, and immunoregulation. Studying the influencing factors for Se enrichment capacity and enrichment mechanisms of Se-enriched probiotics is conducive to the exploit of more potent Se-enriched probiotics. Se-enriched probiotics transform inorganic Se into Se nanoparticles (SeNPs), which have been widely used in animal husbandry and biomedical field. In this paper, the novel development of Se-enriched probiotics is reviewed, and the bioactivities of SeNPs are assessed, so as to display their potential application prospects. The excellent role of SeNPs in anti-oxidation is summarized, and the mechanism by which SeNPs improve Se deficiency and boost animal health is explained. Endemic Se deficiency is a major worldwide nutritional challenge. This review summarizes the functional improvement of Se-enriched probiotics, and discuss their Se enrichment mechanisms. Moreover, a brief summary and the development of Se-enriched probiotics, particularly their potential applications in the field of nutritional additives in food, have been provided.image