Effects of baricitinib, empagliflozin, linagliptin and telmisartan on cardiovascular autonomic neuropathy in type 1 diabetes: An exploratory, randomized, open-label, crossover trial

被引：3

作者：

Laursen, Jens Christian ^{[1
]}

Curovic, Viktor Rotbain ^{[1
]}

Kroonen, Marjolein Y. A. M. ^{[2
]}

Jongs, Niels ^{[2
]}

Zobel, Emilie H. ^{[1
]}

Hansen, Tine W. ^{[1
]}

Frimodt-Moller, Marie ^{[1
]}

Laverman, Gozewijn D. ^{[3
]}

Kooy, Adriaan ^{[4
,5
]}

Persson, Frederik ^{[1
]}

Heerspink, Hiddo J. L. ^{[2
]}

Hansen, Christian Stevns ^{[1
]}

Rossing, Peter ^{[1
,6
]}

机构：

[1] Steno Diabet Ctr Copenhagen, Borgmester Ib Juuls Vej 83, Herlev, Denmark

[2] Univ Groningen, Dept Clin Pharm & Pharmacol, Groningen, Netherlands

[3] Ziekenhuis Grp Twente, Almelo, Netherlands

[4] Bethesda Diabet Res Ctr, Hoogeveen, Netherlands

[5] Univ Groningen, Dept Internal Med, Groningen, Netherlands

[6] Univ Copenhagen, Copenhagen, Denmark

来源：

DIABETES OBESITY & METABOLISM | 2023年 / 25卷 / 10期

关键词：

clinical trial; diabetes complications; diabetic neuropathy; empagliflozin; linagliptin; SGLT2; inhibitor; ALBUMINURIA;

D O I：

10.1111/dom.15180

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：3064 / 3067

页数：4

共 12 条

[1] Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy [J].

Brenner, BM ;

Cooper, ME ;

de Zeeuw, D ;

Keane, WF ;

Mitch, WE ;

Parving, HH ;

Remuzzi, G ;

Snapinn, SM ;

Zhang, ZX ;

Shahinfar, S .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (12) :861-869

[2] Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial [J].

Curovic, Viktor Rotbain ;

Jongs, Niels ;

Kroonen, Marjolein Y. A. M. ;

Zobel, Emilie H. ;

Hansen, Tine W. ;

Sen, Taha ;

Laverman, Gozewijn D. ;

Kooy, Adriaan ;

Persson, Frederik ;

Rossing, Peter ;

Heerspink, Hiddo J. L. .

DIABETES CARE, 2023, 46 (03) :593-601

[3] Efficacy of Administration of an Angiotensin Converting Enzyme Inhibitor for Two Years on Autonomic and Peripheral Neuropathy in Patients with Diabetes Mellitus [J].

Didangelos, Triantafyllos ;

Tziomalos, Konstantinos ;

Margaritidis, Charalambos ;

Kontoninas, Zisis ;

Stergiou, Ioannis ;

Tsotoulidis, Stefanos ;

Karlafti, Eleni ;

Mourouglakis, Alexandros ;

Hatzitolios, Apostolos I. .

JOURNAL OF DIABETES RESEARCH, 2017, 2017

[4] Linagliptin Lowers Albuminuria on Top of Recommended Standard Treatment in Patients With Type 2 Diabetes and Renal Dysfunction [J].

Groop, Per-Henrik ;

Cooper, Mark E. ;

Perkovic, Vlado ;

Emser, Angela ;

Woerle, Hans-Juergen ;

von Eynatten, Maximilian .

DIABETES CARE, 2013, 36 (11) :3460-3468

[5] Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy [J].

Howorka, K ;

Pumprla, J ;

Haber, P ;

KollerStrametz, J ;

Mondrzyk, J ;

Schabmann, A .

CARDIOVASCULAR RESEARCH, 1997, 34 (01) :206-214

[6] Hyperoxia improves autonomic function in individuals with long-duration type 1 diabetes and macroalbuminuria [J].

Laursen, J. C. ;

Hansen, C. S. ;

Bordino, M. ;

Vistisen, D. ;

Zobel, E. H. ;

Winther, S. A. ;

Groop, P-H ;

Frimodt-Moller, M. ;

Bernardi, L. ;

Rossing, P. .

DIABETIC MEDICINE, 2020, 37 (09) :1561-1568

[7] Neuropathy and Related Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study [J].

Martin, Catherine L. ;

Albers, James W. ;

Pop-Busui, Rodica .

DIABETES CARE, 2014, 37 (01) :31-38

[8] Direct renin inhibition improves parasympathetic function in diabetes [J].

Maser, R. E. ;

Lenhard, M. J. ;

Kolm, P. ;

Edwards, D. G. .

DIABETES OBESITY & METABOLISM, 2013, 15 (01) :28-34

[9] The albuminuria-lowering response to dapagliflozin is variable and reproducible among individual patients [J].

Petrykiv, Sergei I. ;

Laverman, Gozewijn D. ;

de Zeeuw, Dick ;

Heerspink, Hiddo J. L. .

DIABETES OBESITY & METABOLISM, 2017, 19 (10) :1363-1370

[10] Diabetic Neuropathy: A Position Statement by the American Diabetes Association [J].

Pop-Busui, Rodica ;

Boulton, Andrew J. M. ;

Feldman, Eva L. ;

Bril, Vera ;

Freeman, Roy ;

Malik, Rayaz A. ;

Sosenko, Jay M. ;

Ziegler, Dan .

DIABETES CARE, 2017, 40 (01) :136-154

← 1 2 →