X-chromosomal STRs in aDNA kinship analysis

被引：1

作者：

Bretschneider, Anna ^{[1
]}

Mazanec, Janine ^{[1
]}

Wittmeier, Patrick ^{[1
]}

Flux, Anna Lena ^{[1
]}

Schmidt, Diane ^{[2
]}

Hummel, Susanne ^{[1
]}

机构：

[1] Univ Gottingen, Dept Hist Anthropol & Human Ecol, Burgerstr 50, D-37073 Gottingen, Germany

[2] Hess Landeskriminalamt, Holderlinstr 1-5, D-65187 Wiesbaden, Germany

来源：

ANTHROPOLOGISCHER ANZEIGER | 2024年 / 81卷 / 02期

关键词：

STR typing; ancient DNA; archaeological skeletal remains; father-daughter relationships; deficiency case; IDENTIFICATION;

D O I：

10.1127/anthranz/2023/1714

中图分类号：

Q98 [人类学];

学科分类号：

030303 ;

摘要：

The analysis of ancient DNA (aDNA) from human skeletal remains can provide useful insights when investigat-ing archaeological finds. One popular application of aDNA is to examine genealogical relationships between individuals recovered at the same archaeological site. For the reconstruction of genealogical relationships, several genetic markers are commonly used: autosomal STRs, mitochondrial lineages (based on SNP-analysis) and Y-chromosomal haplotypes (based on Y-STR-analysis). In this paper, we present the additional opportunities that X-STRs provide in aDNA kinship reconstruction, especially in deficiency cases and for the examination of father-daughter relationships. Possible applica-tions are demonstrated on a range of different kinship reconstructions: confirmation of half-siblingship in the Lichtenstein cave (Germany), exclusion of two potential father-daughter relationships in Goslar (Germany), investigation of three sib-lingships in Boilstadt (Germany) as well as the confirmation of a father-daughter relationship in Stolpe (Germany). This study shows that the analysis of X-STRs can contribute to the investigation of relationship constellations otherwise difficult to approach (e.g. father-daughter relationships) and that X-STRs are useful to support and complement autosomal STRs, mtDNA and Y-STR data.

引用

页码：131 / 138

页数：8

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