Thermophysical Properties of Acetaminophen in Aqueous Solutions of Protic Ionic Liquids Based on Ethanolamine at T=288.15-318.15 K

Proticionic liquids (PILs), a novel category of inexpensive andsustainable solvents, have been employed to solve industrial and medicinesolubility problems. Using a combination of ultrasonic, volumetric,and electrical conductivity methods at 288.15-318.15 K anda pressure of approximate to 87.1 kPa, researchers investigated the thermophysicalproperties of acetaminophen (ACP) in water and aqueous solutions ofthree protic ionic liquids (PILs), which are composed of the cations2-hydroxyethylammonium, bis-(2-hydroxyethyl)-ammonium, and tris-(2-hydroxyethyl)-ammoniumas well as the anion lactate. Study of intermolecular interactionsusing the thermophysical properties is very important because it providesa deep insight into the forces that are functional in the liquid mixtures.For the medication acetaminophen in water and aqueous PIL solutions,thermophysical parameters including apparent molar volume and apparentmolar isentropic compressibility are examined in the current work.The findings showed that interactions between acetaminophen and PILspredominated in the systems under study and that these interactionsincreased as the PIL concentrations rose. The positive transfer resultshave been interpreted using the cosphere overlap model.