Omnipresence MicroRNA-483: A comprehensive organ by organ literature review

被引：1

作者：

Asadi, Mehrdad ^{[1
]}

Zolfi-Gol, Ali ^{[2
]}

Mosarrezaii, Arash ^{[3
]}

Mehran, Shiva ^{[4
]}

Gholinejad, Zafar ^{[5
]}

机构：

[1] Islamic Azad Univ, Fac Med Sci, Dept Med Lab Sci & Microbiol, Tabriz Med Sci, Tabriz, Iran

[2] Urmia Univ Med Sci, Shahid Motahari Hosp, Dept Pediat Cardiol, Orumiyeh, Iran

[3] Urmia Univ Med Sci, Dept Neurol, Orumiyeh, Iran

[4] Higher Educ Inst Rabe Rashidi, Dept Biol, Tabriz, Iran

[5] Islamic Azad Univ, Dept Med Lab Sci, Urmia Branch, Orumiyeh, Iran

来源：

HUMAN GENE | 2023年 / 37卷

关键词：

MiR-483; Cancer; Cardiovascular; Neurologic disorders; Biomarker; SQUAMOUS-CELL CARCINOMA; CIRCULATING MICRORNAS; SERUM MICRORNAS; ALCOHOLIC HEPATITIS; MESENCHYMAL TRANSITION; DIAGNOSTIC BIOMARKERS; EXPRESSION PROFILES; SEQUENCING REVEALS; PLASMA MICRORNA; MIR-483-5P;

D O I：

10.1016/j.humgen.2023.201195

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

MiR-483, insulin-like growth factor 2 gene-derived microRNAs (miRNA), play an important role in the pathogenesis of several diseases in different organs. Serum and tissue levels of miR-483 were proposed as a biomarker for differential diagnosis, prognosis, disease outcome and survival prediction biomarker. Some studies tried to discriminate the function of miR-483 from the function of its host gene, insulin growth factor-2 (IGF-2), and discussed the complex regulation of this transcriptional product. MiR-483 targets the genes in a tissue and organspecific manner. According to the target cell type, miR-483 can induce cell proliferation, cell death, apoptosis, and cell differentiation. In several pathologic conditions, miR-483 levels are up- or down-regulated including cancers, cardiovascular diseases, and neurologic disorders, gynecological disorders and gastrointestinal system. Metabolic disorders and bone metabolism are the other conditions in which miR-483 is involved. In this review, we discuss the miR-483 structure and its clinical importance in the diseases organ by organ.

引用

页数：14

共 173 条

[1] miR-483 targets SMAD4 to suppress chondrogenic differentiation of human mesenchymal stem cells [J].

Anderson, Britta A. ;

McAlinden, Audrey .

JOURNAL OF ORTHOPAEDIC RESEARCH, 2017, 35 (11) :2369-2377

[2] PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells [J].

Arrighetti, Noemi ;

Cossa, Giacomo ;

De Cecco, Loris ;

Stucchi, Simone ;

Carenini, Nives ;

Corna, Elisabetta ;

Gandellini, Paolo ;

Zaffaroni, Nadia ;

Perego, Paola ;

Gatti, Laura .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 310 :9-19

[3] High-Throughput miRNA Sequencing Reveals a Field Effect in Gastric Cancer and Suggests an Epigenetic Network Mechanism [J].

Assumpcao, Monica B. ;

Moreira, Fabiano C. ;

Hamoy, Igor G. ;

Magalhaes, Leandro ;

Vidal, Amanda ;

Pereira, Adenilson ;

Burbano, Rommel ;

Khayat, Andre ;

Silva, Artur ;

Santos, Sidney ;

Demachki, Samia ;

Ribeiro-dos-Santos, Andrea ;

Assumpcao, Paulo .

BIOINFORMATICS AND BIOLOGY INSIGHTS, 2015, 9 :111-117

[4] Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura [J].

Bay, Ali ;

Coskun, Enes ;

Oztuzcu, Serdar ;

Ergun, Sercan ;

Yilmaz, Fatih ;

Aktekin, Elif .

BLOOD COAGULATION & FIBRINOLYSIS, 2014, 25 (04) :379-383

[5] Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma [J].

Bernuzzi, F. ;

Marabita, F. ;

Lleo, A. ;

Carbone, M. ;

Mirolo, M. ;

Marzioni, M. ;

Alpini, G. ;

Alvaro, D. ;

Boberg, K. M. ;

Locati, M. ;

Torzilli, G. ;

Rimassa, L. ;

Piscaglia, F. ;

He, X. -S. ;

Bowlus, C. L. ;

Yang, G. -X. ;

Gershwin, M. E. ;

Invernizzi, P. .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2016, 185 (01) :61-71

[6] CDC25A targeting by miR-483-3p decreases CCND-CDK4/6 assembly and contributes to cell cycle arrest [J].

Bertero, T. ;

Gastaldi, C. ;

Bourget-Ponzio, I. ;

Mari, B. ;

Meneguzzi, G. ;

Barbry, P. ;

Ponzio, G. ;

Rezzonico, R. .

CELL DEATH AND DIFFERENTIATION, 2013, 20 (06) :800-811

[7] Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties [J].

Bertero, Thomas ;

Bourget-Ponzio, Isabelle ;

Puissant, Alexandre ;

Loubat, Agnes ;

Mari, Bernard ;

Meneguzzi, Guerrino ;

Auberger, Patrick ;

Barbry, Pascal ;

Ponzio, Gilles ;

Rezzonico, Roger .

CELL CYCLE, 2013, 12 (14) :2183-2193

[8] miR-483-3p controls proliferation in wounded epithelial cells [J].

Bertero, Thomas ;

Gastaldi, Cecile ;

Bourget-Ponzio, Isabelle ;

Imbert, Veronique ;

Loubat, Agnes ;

Selva, Eric ;

Busca, Roser ;

Mari, Bernard ;

Hofman, Paul ;

Barbry, Pascal ;

Meneguzzi, Guerrino ;

Ponzio, Gilles ;

Rezzonico, Roger .

FASEB JOURNAL, 2011, 25 (09) :3092-3105

[9] Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma [J].

Bi, Chonglei ;

Chung, Tae-Hoon ;

Huang, Gaofeng ;

Zhou, Jianbiao ;

Yan, Junli ;

Ahmann, Gregory J. ;

Fonseca, Rafael ;

Chng, Wee Joo .

ONCOTARGET, 2015, 6 (28) :26508-26518

[10] MicroRNAs and cardiac sarcoplasmic reticulum calcium ATPase-2 in human myocardial infarction: expression and bioinformatic analysis [J].

Bostjancic, Emanuela ;

Zidar, Nina ;

Glavac, Damjan .

BMC GENOMICS, 2012, 13

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