Cp*Co(iii)-catalyzed C-H functionalization/spiroannulation for the synthesis of spiroindenes from 1,3-indandione and alkenes

被引：3

作者：

Xu, Xuefeng ^{[1
]}

Wang, Di ^{[1
]}

Chang, Mengfan ^{[1
]}

Shi, Yue ^{[1
]}

Zhang, Xu ^{[1
]}

机构：

[1] Nanyang Normal Univ, Coll Chem & Pharmaceut Engn, Nanyang 473061, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2023年 / 10卷 / 07期

关键词：

CATALYZED OXIDATIVE ANNULATION; ALKYNES; ACTIVATION; NAPHTHOLS; 2-ALKENYLPHENOLS; DEAROMATIZATION; 1,3-ENYNES; QUINOLINES; ANILINES;

D O I：

10.1039/d3qo00010a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Co(iii)-catalyzed C-H functionalization/spiroannulation of 1,3-indandione with alkenes has been developed for the synthesis of spiroindenes. This efficient protocol features excellent functional group tolerance and highly atom- and step-economy. In this cobalt catalyzed transformation, 1,3-indandione undergoes a facile oxidative dimerization to afford a reactive dimeric intermediate, thus obviating the tedious procedure for the prior preparation of substrates. Furthermore, readily available alkenes, whose compatibility with previous approaches would otherwise be challenging, were well tolerated in this protocol.

引用

页码：1715 / 1720

页数：6

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