Label-Free cancer cell biosensor based on photonic crystal ring resonator

被引:35
作者
Baraty, Fatemeh [1 ]
Hamedi, Samaneh [2 ]
机构
[1] Shiraz Univ Technol, Dept Elect Engn, Shiraz, Iran
[2] Shiraz Univ Technol, Hlth Technol Res Ctr, Shiraz, Iran
关键词
Photonic crystal; Cancer; Refractive index; Ring resonator; Biosensor; WAVE-GUIDE;
D O I
10.1016/j.rinp.2023.106317
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A photonic crystal (PhC) biosensor is a compact device, which detects the changes of characteristic of the light due to binding the sample by the analyte. In this paper; we propose using ring resonator in two-dimensional (2D) photonic crystal biosensor. A periodic array of silicon rods with the refractive index of n = 3.46 in the air bacground formed a cubic lattice structure. The sensing mechanism occures when the the resonant wavelength shifts due to change in the the refractive index of analytes. The transmission spectrum shifts about 4.47 nm to the higher wavelengths by increasing the refractive index of analyte. This mechanism can recognize the normal, and cancerous cells. The average values of sensitivity, quality factor, FOM, and transmission for the designed structure are 308.5 (nm/RIU), 3803.55, 848.06 RIU- 1 and 98.78 %, respectively. The reported structure has high quality promising applications for highly sensitive label-free optical biosensors.
引用
收藏
页数:9
相关论文
共 34 条
[1]  
Amiri IS, 2023, J OPT COMMUN, V44, P139
[2]  
Ayubi-Moak J., 2008, Global modeling of microwave transistors using a full-band Cellular Monte Carlo/full-wave Maxwell simulator
[3]   Computational Study of Photonic Crystal Resonator for Biosensor Application [J].
Benmerkhi, A. ;
Bouchemat, M. ;
Bouchemat, T. .
FREQUENZ, 2019, 73 (9-10) :307-316
[4]   Analysis of one-dimensional photonic crystal based sensor for detection of blood plasma and cancer cells [J].
Bijalwan, Ashish ;
Singh, Bipin K. ;
Rastogi, Vipul .
OPTIK, 2021, 226
[5]   Basal cell carcinoma Basal cell carcinoma Contemporary approaches to diagnosis, treatment, and prevention [J].
Cameron, Michael C. ;
Lee, Erica ;
Hibler, Brian P. ;
Giordano, Cerrene N. ;
Barker, Christopher A. ;
Mori, Shoko ;
Cordova, Miguel ;
Nehal, Kishwer S. ;
Rossi, Anthony M. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2019, 80 (02) :321-339
[6]   Photonic crystal waveguide-based biosensor for detection of diseases [J].
Chopra, Harshita ;
Kaler, Rajinder S. ;
Painam, Balveer .
JOURNAL OF NANOPHOTONICS, 2016, 10 (03)
[7]   Early Changes in Cardiovascular Biomarkers with Contemporary Thoracic Radiation Therapy for Breast Cancer, Lung Cancer, and Lymphoma [J].
Demissei, Biniyam G. ;
Freedman, Gary ;
Feigenberg, Steven J. ;
Plastaras, John P. ;
Maity, Amit ;
Smith, Amanda M. ;
McDonald, Caitlin ;
Sheline, Karyn ;
Simone, Charles B., II ;
Lin, Lilie L. ;
Carver, Joseph R. ;
Liu, Peter ;
Zhang, Liyong ;
Bekelman, Justin E. ;
Ky, Bonnie .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2019, 103 (04) :851-860
[8]  
Farmani Ali, 2020, NANOSENSORS SMART CI, P419, DOI 10.
[9]   Low-power all-optical 8-to-3 encoder using photonic crystal-based waveguides [J].
Haddadan, Fatemeh ;
Soroosh, Mohammad .
PHOTONIC NETWORK COMMUNICATIONS, 2019, 37 (01) :83-89
[10]   Detection of Tumor NTRK Gene Fusions to Identify Patients Who May Benefit from Tyrosine Kinase (TRK) Inhibitor Therapy [J].
Hsiao, Susan J. ;
Zehir, Ahmet ;
Sireci, Anthony N. ;
Aisner, Dara L. .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2019, 21 (04) :553-571