Interdisciplinary Swiss consensus recommendations on staging and treatment of advanced prostate cancer

被引:0
作者
Templeton, Arnoud J. [1 ,2 ,3 ]
Omlin, Aurelius [4 ,5 ]
Berthold, Dominik [6 ]
Beyer, Joerg [7 ]
Burger, Irene A. [8 ]
Eberli, Daniel [9 ]
Engeleri, Daniel [10 ]
Fankhauser, Christian [11 ]
Fischer, Stefanie [12 ]
Gillessen, Silke [13 ]
Nicolas, Guillaume [14 ]
Kroeze, Stephanie [15 ]
Lorch, Anja [16 ]
Muentener, Michael [17 ]
Papachristofilou, Alexandros [18 ]
Schaefer, Niklaus [19 ]
Seiler, Daniel [20 ]
Stenner, Frank [21 ]
Tsantoulis, Petros [22 ]
Vlajnic, Tatjana [23 ,24 ]
Zilli, Thomas [25 ]
Zwahlen, Daniel [26 ]
Cathomas, Richard [27 ]
机构
[1] St Clara Hosp, Med Oncol, Basel, Switzerland
[2] St Clara Res Ltd, Basel, Switzerland
[3] Univ Basel, Fac Med, Basel, Switzerland
[4] Univ Zurich, Onkozentrum Zurich, Zurich, Switzerland
[5] Tumorzentrum Hirslanden Zurich, Zurich, Switzerland
[6] CHUV Lausanne, Med Oncol, Vaud, Switzerland
[7] Inselspital Bern, Med Oncol, Univ Spital, Bern, Switzerland
[8] Kantonsspital Baden, Dept Nucl Med, Baden, Switzerland
[9] Univ Spital Zurich, Dept Urol, Zurich, Switzerland
[10] Kantonsspital St Gallen, Dept Urol, St Gallen, Switzerland
[11] Luzerner Kantonsspital, Dept Urol, Luzern, Switzerland
[12] Kantonsspital St Gallen, Dept Med Oncol & Hematol, St Gallen, Switzerland
[13] Ente Osped Cantonale EOC, Med Oncol, Bellinzona, Switzerland
[14] Univ Spital Basel, Dept Nucl Med, Basel, Switzerland
[15] Kantonsspital Aarau, Dept Radiooncol, Aarau, Switzerland
[16] Univ Spital Zurich, Med Oncol & Hematol, Zurich, Switzerland
[17] Stadtspital Zurich Triemli, Dept Urol, Zurich, Switzerland
[18] Univ Spital Basel, Dept Radiooncol, Basel, Switzerland
[19] CHU Vaudois, Dept Visceral Surg, Lausanne, Vaud, Switzerland
[20] Rotes Schloss Zurich, Dept Urol, Zurich, Switzerland
[21] Univ Spital Basel, Med Oncol & Hematol, Basel, Switzerland
[22] Univ Geneve HUG, Med Oncol & Hematol, Geneva, Switzerland
[23] Kantonsspital Graubunden, Inst Pathol, Chur, Switzerland
[24] Univ Spital Basel, Inst Med Genet & Pathol, Basel, Switzerland
[25] Ente Osped Cantonale EOC, Dept Radiooncol, Bellinzona, Switzerland
[26] Kantonsspital Winterthur, Dept Radiooncol, Winterthur, Switzerland
[27] Kantonsspital Graubunden, Div Hematol Oncol, Chur, Switzerland
关键词
THERAPY;
D O I
10.57187/smw.2023.40108
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The management of prostate cancer is undergoing rapid changes in all disease settings. Novel imaging tools for diagnosis have been introduced, and the treatment of high-risk localized, locally advanced and metastatic disease has changed considerably in recent years. From clinical and health-economic perspectives, a rational and optimal use of the available options is of the utmost importance. While international guidelines list relevant pivotal trials and give recommendations for a variety of clinical scenarios, there is much room for interpretation, and several important questions remain highly debated. The goal of developing a national consensus on the use of these novel diagnostic and therapeutic strategies in order to improve disease management and eventually patient outcomes has prompted a Swiss consensus meeting. Experts from several specialties, including urology, medical oncology, radiation oncology, pathology and nuclear medicine, discussed and voted on questions of the current most important areas of uncertainty, including the staging and treatment of high-risk localized disease, treatment of metastatic hormone-sensitive prostate cancer (mHSPC) and use of new options to treat metastatic castration-resistant prostate cancer (mCRPC).
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